Mycobacterium africanum--review of an important cause of human tuberculosis in West Africa

BC de Jong; M Antonio; S Gagneux

doi:10.1371/journal.pntd.0000744

Mycobacterium africanum--review of an important cause of human tuberculosis in West Africa

BC de Jong, M Antonio, S Gagneux

Research output: Contribution to journal › A1: Web of Science-article › peer-review

Abstract

Mycobacterium africanum consists of two phylogenetically distinct lineages within the Mycobacterium tuberculosis complex, known as M. africanum West African 1 and M. africanum West African 2. These lineages are restricted to West Africa, where they cause up to half of human pulmonary tuberculosis. In this review we discuss the definition of M. africanum, describe the prevalence and restricted geographical distribution of M. africanum West African 1 and 2, review the occurrence of M. africanum in animals, and summarize the phenotypic differences described thus far between M. africanum and M. tuberculosis sensu stricto

Original language	English
Journal	PLoS Neglected Tropical Diseases
Volume	4
Issue number	9
Pages (from-to)	e744
Number of pages	9
ISSN	1935-2727
DOIs	https://doi.org/10.1371/journal.pntd.0000744
Publication status	Published - 2010

Keywords

B780-tropical-medicine
Bacterial diseases
Pulmonary
Tuberculosis
Mycobacterium africanum
Mycobacterium tuberculosis
Prevalence
Epidemiology
Phylogeny
Case definition
Nomenclature
Geographical distribution
Occurrence
Phenotypes
Clinical manifestations
Review of the literature

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10.1371/journal.pntd.0000744

http://lib.itg.be/pdf/itg/2010/2010pntde744.pdf

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title = "Mycobacterium africanum--review of an important cause of human tuberculosis in West Africa",

abstract = "Mycobacterium africanum consists of two phylogenetically distinct lineages within the Mycobacterium tuberculosis complex, known as M. africanum West African 1 and M. africanum West African 2. These lineages are restricted to West Africa, where they cause up to half of human pulmonary tuberculosis. In this review we discuss the definition of M. africanum, describe the prevalence and restricted geographical distribution of M. africanum West African 1 and 2, review the occurrence of M. africanum in animals, and summarize the phenotypic differences described thus far between M. africanum and M. tuberculosis sensu stricto",

keywords = "B780-tropical-medicine, Bacterial diseases, Pulmonary, Tuberculosis, Mycobacterium africanum, Mycobacterium tuberculosis, Prevalence, Epidemiology, Phylogeny, Case definition, Nomenclature, Geographical distribution, Occurrence, Phenotypes, Clinical manifestations, Review of the literature",

author = "{de Jong}, BC and M Antonio and S Gagneux",

note = "ITG-M1A; MICRO; U-MYCOB; JIF; DOI; PDF; Abstract; E-only; DSPACE",

year = "2010",

doi = "10.1371/journal.pntd.0000744",

language = "English",

volume = "4",

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journal = "PLoS Neglected Tropical Diseases",

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T1 - Mycobacterium africanum--review of an important cause of human tuberculosis in West Africa

AU - de Jong, BC

AU - Antonio, M

AU - Gagneux, S

N1 - ITG-M1A; MICRO; U-MYCOB; JIF; DOI; PDF; Abstract; E-only; DSPACE

PY - 2010

Y1 - 2010

N2 - Mycobacterium africanum consists of two phylogenetically distinct lineages within the Mycobacterium tuberculosis complex, known as M. africanum West African 1 and M. africanum West African 2. These lineages are restricted to West Africa, where they cause up to half of human pulmonary tuberculosis. In this review we discuss the definition of M. africanum, describe the prevalence and restricted geographical distribution of M. africanum West African 1 and 2, review the occurrence of M. africanum in animals, and summarize the phenotypic differences described thus far between M. africanum and M. tuberculosis sensu stricto

AB - Mycobacterium africanum consists of two phylogenetically distinct lineages within the Mycobacterium tuberculosis complex, known as M. africanum West African 1 and M. africanum West African 2. These lineages are restricted to West Africa, where they cause up to half of human pulmonary tuberculosis. In this review we discuss the definition of M. africanum, describe the prevalence and restricted geographical distribution of M. africanum West African 1 and 2, review the occurrence of M. africanum in animals, and summarize the phenotypic differences described thus far between M. africanum and M. tuberculosis sensu stricto

KW - B780-tropical-medicine

KW - Bacterial diseases

KW - Pulmonary

KW - Tuberculosis

KW - Mycobacterium africanum

KW - Mycobacterium tuberculosis

KW - Prevalence

KW - Epidemiology

KW - Phylogeny

KW - Case definition

KW - Nomenclature

KW - Geographical distribution

KW - Occurrence

KW - Phenotypes

KW - Clinical manifestations

KW - Review of the literature

U2 - 10.1371/journal.pntd.0000744

DO - 10.1371/journal.pntd.0000744

M3 - A1: Web of Science-article

C2 - 20927191

SN - 1935-2727

VL - 4

SP - e744

JO - PLoS Neglected Tropical Diseases

JF - PLoS Neglected Tropical Diseases

IS - 9

ER -

Mycobacterium africanum--review of an important cause of human tuberculosis in West Africa

Abstract

Keywords

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