Enterovirus detection in stool samples from Mozambican children with acute gastroenteritis

DM Bero, EE da Silva, IP de Sousa, SA Nhassengo, RS Machado, AFL Bauhofer, JJ Chilaúle, B Munlela, E Guimaraes, I Cossa-Moiane, J Sambo, E Anapakala, M Cassocera, L Coutinho-Manhique, A Chissaque, JS Langa, F Burlandy, N de Deus

    Research output: Contribution to journalA1: Web of Science-articlepeer-review


    Enteroviruses (EV) are predominantly enteric viruses, present in all parts of the world causing disease in humans with a broad spectrum of clinical presentations. The purpose of this study was to identify non-polio enteroviruses (NPEV) in stool samples collected from children with acute gastroenteritis (AGE) symptoms of unknown etiology in four provinces (Maputo, Nampula, Sofala and Zambézia) of Mozambique. From June 2014 to March 2018, 327 stool samples were collected from children hospitalized with AGE in health care units. NPEVs were detected in 52 samples (52/327; 15.9%) and were more frequent in children under 5 years of age. The age group from 12 to 23 months was the most affected and showed more severity of disease. We also identified 26 different EV-types with the following detection pattern EV-B>EV-C>EV-A. The major EV-types were EV-A119 (9/52; 17.3%) and EV-C99 (8/52; 15.4%), accounting for 32.7% of the total. In addition to EV-A119, other uncommon EV-types were also identified, such as EV-B75, EV-B97 and EV-C113. The current study shows a high heterogeneity of EV types circulating in children with AGE in Mozambique as well as the identification of rarely described enteroviruses.
    Original languageEnglish
    Article number106755
    JournalActa Tropica
    Number of pages5
    Publication statusPublished - 2023


    • Children
    • Diarrheal disease
    • Enterovirus
    • Gastroenteritis
    • Mozambique


    Dive into the research topics of 'Enterovirus detection in stool samples from Mozambican children with acute gastroenteritis'. Together they form a unique fingerprint.

    Cite this