Epidemic spread of plasmid-mediated tetracycline resistant Neisseria gonorrhoeae in Zaire

E Van Dyck, M Laga, TM Abib, F Behets, P Piot

Research output: Contribution to journalA1: Web of Science-article

Abstract

A cohort of 650 prostitutes from Kinshasa, Zaire, was followed at monthly intervals for sexually transmitted diseases as part of an HIV intervention project. Neisseria gonorrhoeae isolates, obtained during a period of 30 months, were auxotyped, serotyped and tested for antimicrobial susceptibility. Among 1085 gonococcal isolates tested, 725 (67%) produced beta-lactamase (PPNG) and 323 (30%) showed plasmid-mediated resistance to tetracyline (TRNG). Over time, the prevalence of PPNG varied between 60 and 73%, while the level of TRNG increased from 11 to 45%
Original languageEnglish
JournalInternational Journal of STD & AIDS
Volume6
Pages (from-to)345-347
ISSN0956-4624
Publication statusPublished - 1995

Keywords

  • B780-tropical-medicine
  • Bacterial diseases
  • Gonorrhea
  • Neisseria gonorrhoeae
  • Drug resistance
  • Tetracycline
  • STD
  • Sexually transmitted diseases
  • Prostitutes
  • PPNG
  • Prevalence
  • Congo-Kinshasa
  • Kinshasa
  • Africa-Central

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