TY - JOUR
T1 - Epidemiological characteristics of monkeypox virus Clade Ib in the Democratic Republic of the Congo
AU - Kremer, Cecile
AU - Nundu, Sabin Sabiti
AU - Vakaniaki, Emmanuel Hasivirwe
AU - Brosius, Isabel
AU - Mukari, Guy
AU - Munganga, Papy
AU - Bangwen, Eugene
AU - Tshomba, Jean Claude
AU - Mujula, Yves
AU - De Vos, Elise
AU - Van Dijck, Christophe
AU - Houben, Sarah
AU - Gressani, Oswaldo
AU - Kacita, Cris
AU - Mukadi-Bamuleka, Daniel
AU - Wawina-Bokalanga, Tony
AU - Kinganda-Lusamaki, Eddy
AU - Amuri-Aziza, Adrienne
AU - Lupola, Patrick Mutombo
AU - Muyembe-Tamfum, Jean-Jacques
AU - Mbala-Kingebeni, Placide
AU - Liesenborghs, Laurens
AU - Hens, Niel
AU - Torneri, Andrea
N1 - FTX; DOAJ; CC BY NC ND
PY - 2025/12
Y1 - 2025/12
N2 - Monkeypox virus (MPXV) Clade Ib, a new MPXV subclade associated with sustained human-to-human transmission, emerged in eastern DRC in late 2023. Early spread mainly occurred among the adult population, primarily through sexual contact. We investigate how key epidemiological characteristics of the new MPXV Clade Ib outbreak in the DRC differ by transmission mode. We estimate the mean serial interval to be 8.57 days (95% CI 7.15 − 9.91 days). The serial interval is approximately four days shorter for putative sexual compared to non-sexual transmission. We estimate the mean incubation period to be 9.56 days (95% CrI 8.22 − 11.02 days), and approximately two days shorter for putative sexual compared to non-sexual transmission. These observed differences in serial interval and incubation period estimates by transmission mode suggest that the context in which an outbreak occurs is an essential factor to consider when devising public health policies.
AB - Monkeypox virus (MPXV) Clade Ib, a new MPXV subclade associated with sustained human-to-human transmission, emerged in eastern DRC in late 2023. Early spread mainly occurred among the adult population, primarily through sexual contact. We investigate how key epidemiological characteristics of the new MPXV Clade Ib outbreak in the DRC differ by transmission mode. We estimate the mean serial interval to be 8.57 days (95% CI 7.15 − 9.91 days). The serial interval is approximately four days shorter for putative sexual compared to non-sexual transmission. We estimate the mean incubation period to be 9.56 days (95% CrI 8.22 − 11.02 days), and approximately two days shorter for putative sexual compared to non-sexual transmission. These observed differences in serial interval and incubation period estimates by transmission mode suggest that the context in which an outbreak occurs is an essential factor to consider when devising public health policies.
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=itm_wosliteitg&SrcAuth=WosAPI&KeyUT=WOS:001656367700001&DestLinkType=FullRecord&DestApp=WOS_CPL
U2 - 10.1038/s41467-025-66875-6
DO - 10.1038/s41467-025-66875-6
M3 - A1: Peer-reviewed journal articles
C2 - 41353437
SN - 2041-1723
VL - 17
JO - Nature Communications
JF - Nature Communications
IS - 1
M1 - 180
ER -