TY - JOUR
T1 - Estimating the percentage of European MSM eligible for PrEP: insights from a bio-behavioural survey in thirteen cities
AU - Cordioli, Maddalena
AU - Gios, Lorenzo
AU - Huber, Jorg W.
AU - Sherriff, Nigel
AU - Folch, Cinta
AU - Alexiev, Ivailo
AU - Dias, Sonia
AU - Nöstlinger, Christiana
AU - Gama, Ana
AU - Naseva, Emilia
AU - Stanekova, Danica Valkovicova
AU - Marcus, Ulrich
AU - Schink, Susanne Barbara
AU - Rosinska, Magdalena
AU - Blondeel, Karel
AU - Toskin, Igor
AU - Mirandola, Massimo
N1 - FTX; OGOA
PY - 2021
Y1 - 2021
N2 - Objectives This paper aims to estimate the percentage of European men who have sex with men (MSM) who may benefit from pre-exposure prophylaxis (PrEP), applying the three most widely used HIV risk indices for MSM (MSM Risk Index, Menza score, San Diego Early Test (SDET) score) and drawing on a large-scale multisite bio-behavioural survey (Sialon II). Methods The Sialon II study was a bio-behavioural survey among MSM implemented in 13 European cities using either time-location sampling or respondent-driven sampling. Biological and behavioural data from 4901 MSM were collected. Only behavioural data of HIV-negative individuals were considered. Three widely used risk indices to assess HIV acquisition risk among MSM were used to estimate individual HIV risk scores and PrEP eligibility criteria. Results 4219 HIV-negative MSM were considered. Regardless the HIV risk score used and the city, percentages of MSM eligible for PrEP were found to range between 5.19% and 73.84%. Overall, the MSM Risk Index and the Menza score yielded broadly similar percentages, whereas the SDET Index provided estimates constantly lower across all cities. Although all the three scores correlated positively (r>0.6), their concordance was highly variable (0.01
AB - Objectives This paper aims to estimate the percentage of European men who have sex with men (MSM) who may benefit from pre-exposure prophylaxis (PrEP), applying the three most widely used HIV risk indices for MSM (MSM Risk Index, Menza score, San Diego Early Test (SDET) score) and drawing on a large-scale multisite bio-behavioural survey (Sialon II). Methods The Sialon II study was a bio-behavioural survey among MSM implemented in 13 European cities using either time-location sampling or respondent-driven sampling. Biological and behavioural data from 4901 MSM were collected. Only behavioural data of HIV-negative individuals were considered. Three widely used risk indices to assess HIV acquisition risk among MSM were used to estimate individual HIV risk scores and PrEP eligibility criteria. Results 4219 HIV-negative MSM were considered. Regardless the HIV risk score used and the city, percentages of MSM eligible for PrEP were found to range between 5.19% and 73.84%. Overall, the MSM Risk Index and the Menza score yielded broadly similar percentages, whereas the SDET Index provided estimates constantly lower across all cities. Although all the three scores correlated positively (r>0.6), their concordance was highly variable (0.01
KW - pre-exposure prophylaxis
KW - sexual behaviour
KW - HIV
KW - preventive health services
KW - public health
KW - PREEXPOSURE PROPHYLAXIS
KW - HIV-INFECTION
KW - MEN
KW - SEX
KW - RISK
U2 - 10.1136/sextrans-2020-054786
DO - 10.1136/sextrans-2020-054786
M3 - A1: Web of Science-article
SN - 1368-4973
VL - 97
SP - 534
EP - 540
JO - Sexually Transmitted Infections
JF - Sexually Transmitted Infections
IS - 7
ER -