Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice

A. Soto, D. Salazar, V. Acurio, P. Segura, P. Van der Stuyft

    Research output: Contribution to journalA1: Web of Science-article

    Abstract

    We evaluated the diagnostic yield of fiberoptic bronchoscopy for the diagnosis of smear-negative pulmonary tuberculosis in patients treated at a referral hospital in Lima, Peru. Of the 611 patients who underwent the procedure, 140 (23%) were diagnosed with tuberculosis based on the analysis of BAL samples. Being young and being male were significantly associated with positive cultures. In addition, 287 patients underwent post-bronchoscopic sputum smear testing for AFB, the results of which increased the diagnostic yield by 22% over that obtained through the analysis of BAL samples alone. We conclude that the analysis of BAL samples and post-bronchoscopic sputum samples provides a high diagnostic yield in smear-negative patients suspected of having pulmonary tuberculosis.
    Original languageSpanish
    JournalJornal Brasileiro de Pneumologia
    Volume38
    Issue number6
    Pages (from-to)757-760
    Number of pages4
    ISSN1806-3713
    DOIs
    Publication statusPublished - 2012

    Keywords

    • Bacterial diseases
    • Pulmonary
    • Tuberculosis
    • Mycobacterium tuberculosis
    • Routine
    • Clinical management
    • Smear-negative
    • Sputum
    • Diagnosis
    • Evaluation
    • Bronchoscopy
    • Peru
    • America-Latin
    • Author

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