Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice

A. Soto; D. Salazar; V. Acurio; P. Segura; P. Van der Stuyft

doi:10.1590/S1806-37132012000600011

Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice

Translated title of the contribution: Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice

A. Soto, D. Salazar, V. Acurio, P. Segura, P. Van der Stuyft

Research output: Contribution to journal › A1: Web of Science-article › peer-review

Abstract

We evaluated the diagnostic yield of fiberoptic bronchoscopy for the diagnosis of smear-negative pulmonary tuberculosis in patients treated at a referral hospital in Lima, Peru. Of the 611 patients who underwent the procedure, 140 (23%) were diagnosed with tuberculosis based on the analysis of BAL samples. Being young and being male were significantly associated with positive cultures. In addition, 287 patients underwent post-bronchoscopic sputum smear testing for AFB, the results of which increased the diagnostic yield by 22% over that obtained through the analysis of BAL samples alone. We conclude that the analysis of BAL samples and post-bronchoscopic sputum samples provides a high diagnostic yield in smear-negative patients suspected of having pulmonary tuberculosis.

Translated title of the contribution	Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice
Original language	Spanish
Journal	Jornal Brasileiro de Pneumologia
Volume	38
Issue number	6
Pages (from-to)	757-760
Number of pages	4
ISSN	1806-3713
DOIs	https://doi.org/10.1590/S1806-37132012000600011
Publication status	Published - 2012

Keywords

Bacterial diseases
Pulmonary
Tuberculosis
Mycobacterium tuberculosis
Routine
Clinical management
Smear-negative
Sputum
Diagnosis
Evaluation
Bronchoscopy
Peru
America-Latin
Author

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10.1590/S1806-37132012000600011

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title = "Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice",

abstract = "We evaluated the diagnostic yield of fiberoptic bronchoscopy for the diagnosis of smear-negative pulmonary tuberculosis in patients treated at a referral hospital in Lima, Peru. Of the 611 patients who underwent the procedure, 140 (23%) were diagnosed with tuberculosis based on the analysis of BAL samples. Being young and being male were significantly associated with positive cultures. In addition, 287 patients underwent post-bronchoscopic sputum smear testing for AFB, the results of which increased the diagnostic yield by 22% over that obtained through the analysis of BAL samples alone. We conclude that the analysis of BAL samples and post-bronchoscopic sputum samples provides a high diagnostic yield in smear-negative patients suspected of having pulmonary tuberculosis.",

keywords = "Bacterial diseases, Pulmonary, Tuberculosis, Mycobacterium tuberculosis, Routine, Clinical management, Smear-negative, Sputum, Diagnosis, Evaluation, Bronchoscopy, Peru, America-Latin, Author",

author = "A. Soto and D. Salazar and V. Acurio and P. Segura and {Van der Stuyft}, P.",

note = "M1 - J Bras Pneumol",

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doi = "10.1590/S1806-37132012000600011",

language = "Spanish",

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pages = "757--760",

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TY - JOUR

T1 - Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice

AU - Soto, A.

AU - Salazar, D.

AU - Acurio, V.

AU - Segura, P.

AU - Van der Stuyft, P.

N1 - M1 - J Bras Pneumol

PY - 2012

Y1 - 2012

N2 - We evaluated the diagnostic yield of fiberoptic bronchoscopy for the diagnosis of smear-negative pulmonary tuberculosis in patients treated at a referral hospital in Lima, Peru. Of the 611 patients who underwent the procedure, 140 (23%) were diagnosed with tuberculosis based on the analysis of BAL samples. Being young and being male were significantly associated with positive cultures. In addition, 287 patients underwent post-bronchoscopic sputum smear testing for AFB, the results of which increased the diagnostic yield by 22% over that obtained through the analysis of BAL samples alone. We conclude that the analysis of BAL samples and post-bronchoscopic sputum samples provides a high diagnostic yield in smear-negative patients suspected of having pulmonary tuberculosis.

AB - We evaluated the diagnostic yield of fiberoptic bronchoscopy for the diagnosis of smear-negative pulmonary tuberculosis in patients treated at a referral hospital in Lima, Peru. Of the 611 patients who underwent the procedure, 140 (23%) were diagnosed with tuberculosis based on the analysis of BAL samples. Being young and being male were significantly associated with positive cultures. In addition, 287 patients underwent post-bronchoscopic sputum smear testing for AFB, the results of which increased the diagnostic yield by 22% over that obtained through the analysis of BAL samples alone. We conclude that the analysis of BAL samples and post-bronchoscopic sputum samples provides a high diagnostic yield in smear-negative patients suspected of having pulmonary tuberculosis.

KW - Bacterial diseases

KW - Pulmonary

KW - Tuberculosis

KW - Mycobacterium tuberculosis

KW - Routine

KW - Clinical management

KW - Smear-negative

KW - Sputum

KW - Diagnosis

KW - Evaluation

KW - Bronchoscopy

KW - Peru

KW - America-Latin

KW - Author

U2 - 10.1590/S1806-37132012000600011

DO - 10.1590/S1806-37132012000600011

M3 - A1: Web of Science-article

SN - 1806-3713

VL - 38

SP - 757

EP - 760

JO - Jornal Brasileiro de Pneumologia

JF - Jornal Brasileiro de Pneumologia

IS - 6

ER -

Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice

Abstract

Keywords

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