Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice

A. Soto, D. Salazar, V. Acurio, P. Segura, P. Van der Stuyft

Research output: Contribution to journalA1: Web of Science-article

Abstract

We evaluated the diagnostic yield of fiberoptic bronchoscopy for the diagnosis of smear-negative pulmonary tuberculosis in patients treated at a referral hospital in Lima, Peru. Of the 611 patients who underwent the procedure, 140 (23%) were diagnosed with tuberculosis based on the analysis of BAL samples. Being young and being male were significantly associated with positive cultures. In addition, 287 patients underwent post-bronchoscopic sputum smear testing for AFB, the results of which increased the diagnostic yield by 22% over that obtained through the analysis of BAL samples alone. We conclude that the analysis of BAL samples and post-bronchoscopic sputum samples provides a high diagnostic yield in smear-negative patients suspected of having pulmonary tuberculosis.
Original languageSpanish
JournalJornal Brasileiro de Pneumologia
Volume38
Issue number6
Pages (from-to)757-760
Number of pages4
ISSN1806-3713
DOIs
Publication statusPublished - 2012

Keywords

  • Bacterial diseases
  • Pulmonary
  • Tuberculosis
  • Mycobacterium tuberculosis
  • Routine
  • Clinical management
  • Smear-negative
  • Sputum
  • Diagnosis
  • Evaluation
  • Bronchoscopy
  • Peru
  • America-Latin
  • Author

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