Evidence-based vector control? Improving the quality of vector control trials

Anne L Wilson, Marleen Boelaert, Immo Kleinschmidt, Margaret Pinder, Thomas W Scott, Lucy S Tusting, Steve W Lindsay

    Research output: Contribution to journalA1: Web of Science-article

    Abstract

    Vector-borne diseases (VBDs) such as malaria, dengue, and leishmaniasis cause a high level of morbidity and mortality. Although vector control tools can play a major role in controlling and eliminating these diseases, in many cases the evidence base for assessing the efficacy of vector control interventions is limited or not available. Studies assessing the efficacy of vector control interventions are often poorly conducted, which limits the return on investment of research funding. Here we outline the principal design features of Phase III vector control field studies, highlight major failings and strengths of published studies, and provide guidance on improving the design and conduct of vector control studies. We hope that this critical assessment will increase the impetus for more carefully considered and rigorous design of vector control studies.

    Original languageEnglish
    JournalTrends In Parasitology
    Volume31
    Issue number8
    Pages (from-to)380-390
    ISSN1471-4922
    DOIs
    Publication statusPublished - 2015

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