Experimental induction of paromomycin resistance in antimony-resistant strains of L. donovani: outcome dependent on in vitro selection protocol

S. Hendrickx; R.A. Inocêncio da Luz; V. Bhandari; K. Kuypers; C.D. Shaw; J. Lonchamp; P. Salotra; K. Carter; S. Sundar; S. Rijal; J.C. Dujardin; P. Cos; L. Maes

doi:10.1371/journal.pntd.0001664

Experimental induction of paromomycin resistance in antimony-resistant strains of L. donovani: outcome dependent on in vitro selection protocol

S. Hendrickx, R.A. Inocêncio da Luz, V. Bhandari, K. Kuypers, C.D. Shaw, J. Lonchamp, P. Salotra, K. Carter, S. Sundar, S. Rijal, J.C. Dujardin, P. Cos, L. Maes

Molecular Parasitology

Research output: Contribution to journal › A1: Web of Science-article › peer-review

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Original language	English
Journal	PLoS Neglected Tropical Diseases
Volume	6
Issue number	5
Pages (from-to)	e1664
ISSN	1935-2727
DOIs	https://doi.org/10.1371/journal.pntd.0001664
Publication status	Published - 2012

Keywords

Protozoal diseases
Visceral
Leishmaniasis
Kala azar
Leishmania donovani
Vectors
Sandflies
Phlebotomus argentipes
Treatment
Drug resistance
Paromomycin
Antimony
In vitro
Protocols
Culture
Comparison
Drug susceptibility
Stability
Promastigotes
Intracellular
Amastigotes
Clones
Strains
Phenotypes
Laboratory techniques and procedures

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Cite this

Hendrickx, S., Inocêncio da Luz, R. A., Bhandari, V., Kuypers, K., Shaw, C. D., Lonchamp, J., Salotra, P., Carter, K., Sundar, S., Rijal, S., Dujardin, J. C., Cos, P., & Maes, L. (2012). Experimental induction of paromomycin resistance in antimony-resistant strains of L. donovani: outcome dependent on in vitro selection protocol. PLoS Neglected Tropical Diseases, 6(5), e1664. https://doi.org/10.1371/journal.pntd.0001664

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title = "Experimental induction of paromomycin resistance in antimony-resistant strains of L. donovani: outcome dependent on in vitro selection protocol",

keywords = "Protozoal diseases, Visceral, Leishmaniasis, Kala azar, Leishmania donovani, Vectors, Sandflies, Phlebotomus argentipes, Treatment, Drug resistance, Paromomycin, Antimony, In vitro, Protocols, Culture, Comparison, Drug susceptibility, Stability, Promastigotes, Intracellular, Amastigotes, Clones, Strains, Phenotypes, Laboratory techniques and procedures",

author = "S. Hendrickx and {Inoc{\^e}ncio da Luz}, R.A. and V. Bhandari and K. Kuypers and C.D. Shaw and J. Lonchamp and P. Salotra and K. Carter and S. Sundar and S. Rijal and J.C. Dujardin and P. Cos and L. Maes",

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Hendrickx, S, Inocêncio da Luz, RA, Bhandari, V, Kuypers, K, Shaw, CD, Lonchamp, J, Salotra, P, Carter, K, Sundar, S, Rijal, S, Dujardin, JC, Cos, P & Maes, L 2012, 'Experimental induction of paromomycin resistance in antimony-resistant strains of L. donovani: outcome dependent on in vitro selection protocol', PLoS Neglected Tropical Diseases, vol. 6, no. 5, pp. e1664. https://doi.org/10.1371/journal.pntd.0001664

TY - JOUR

T1 - Experimental induction of paromomycin resistance in antimony-resistant strains of L. donovani: outcome dependent on in vitro selection protocol

AU - Hendrickx, S.

AU - Inocêncio da Luz, R.A.

AU - Bhandari, V.

AU - Kuypers, K.

AU - Shaw, C.D.

AU - Lonchamp, J.

AU - Salotra, P.

AU - Carter, K.

AU - Sundar, S.

AU - Rijal, S.

AU - Dujardin, J.C.

AU - Cos, P.

AU - Maes, L.

N1 - ITG-B11A; DBM; U-MOLPAR; JIF; DOI; PDF; E-only; DSPACE

PY - 2012

Y1 - 2012

KW - Protozoal diseases

KW - Visceral

KW - Leishmaniasis

KW - Kala azar

KW - Leishmania donovani

KW - Vectors

KW - Sandflies

KW - Phlebotomus argentipes

KW - Treatment

KW - Drug resistance

KW - Paromomycin

KW - Antimony

KW - In vitro

KW - Protocols

KW - Culture

KW - Comparison

KW - Drug susceptibility

KW - Stability

KW - Promastigotes

KW - Intracellular

KW - Amastigotes

KW - Clones

KW - Strains

KW - Phenotypes

KW - Laboratory techniques and procedures

U2 - 10.1371/journal.pntd.0001664

DO - 10.1371/journal.pntd.0001664

M3 - A1: Web of Science-article

C2 - 22666513

SN - 1935-2727

VL - 6

SP - e1664

JO - PLoS Neglected Tropical Diseases

JF - PLoS Neglected Tropical Diseases

IS - 5

ER -