Family history: an opportunity for early interventions and improved control of hypertension, obesity and diabetes

M A van der Sande; G E Walraven; P J Milligan; W A Banya; S M Ceesay; O A Nyan; K P McAdam

Family history: an opportunity for early interventions and improved control of hypertension, obesity and diabetes

M A van der Sande, G E Walraven, P J Milligan, W A Banya, S M Ceesay, O A Nyan, K P McAdam

Department of Public Health

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Abstract

OBJECTIVE: To examine whether a family history of high-risk groups for major noncommunicable diseases (NCDs) was a significant risk factor for these conditions among family members in a study population in the Gambia, where strong community and family coherence are important determinants that have to be taken into consideration in promoting lifestyle changes.

METHODS: We questioned 5389 adults as to any first-degree family history of major noncommunicable diseases (hypertension, obesity, diabetes and stroke), and measured their blood pressure (BP) and body mass index (BMI). Total blood cholesterol, triglyceride, uric acid, and creatinine concentrations were measured in a stratified subsample, as well as blood glucose (2 hours after ingesting 75 g glucose) in persons aged > or = 35 years.

FINDINGS: A significant number of subjects reported a family history of hypertension (8.0%), obesity (5.4%), diabetes (3.3%) and stroke (1.4%), with 14.6% of participants reporting any of these NCDs. Subjects with a family history of hypertension had a higher diastolic BP and BMI, higher cholesterol and uric acid concentrations, and an increased risk of obesity. Those with a family history of obesity had a higher BMI and were at increased risk of obesity. Individuals with a family history of diabetes had a higher BMI and higher concentrations of glucose, cholesterol, triglycerides and uric acid, and their risk of obesity and diabetes was increased. Subjects with a family history of stroke had a higher BMI, as well as higher cholesterol, triglyceride and uric acid concentrations.

CONCLUSIONS: A family history of hypertension, obesity, diabetes, or stroke was a significant risk factor for obesity and hyperlipidaemia. With increase of age, more pathological manifestations can develop in this high-risk group. Health professionals should therefore utilize every opportunity to include direct family members in health education.

Original language	English
Journal	Bulletin of the World Health Organization
Volume	79
Issue number	4
Pages (from-to)	321-328
Number of pages	8
ISSN	0042-9686
Publication status	Published - 2001

Keywords

Adult
Diabetes Mellitus/epidemiology
Family Health
Female
Gambia/epidemiology
Genetic Predisposition to Disease
Humans
Hypertension/epidemiology
Medical History Taking
Middle Aged
Obesity/epidemiology
Risk Factors

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2001bwho0321Final published version, 300 KBLicence: CC BY

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566400/Licence: CC BY

Cite this

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title = "Family history: an opportunity for early interventions and improved control of hypertension, obesity and diabetes",

abstract = "OBJECTIVE: To examine whether a family history of high-risk groups for major noncommunicable diseases (NCDs) was a significant risk factor for these conditions among family members in a study population in the Gambia, where strong community and family coherence are important determinants that have to be taken into consideration in promoting lifestyle changes.METHODS: We questioned 5389 adults as to any first-degree family history of major noncommunicable diseases (hypertension, obesity, diabetes and stroke), and measured their blood pressure (BP) and body mass index (BMI). Total blood cholesterol, triglyceride, uric acid, and creatinine concentrations were measured in a stratified subsample, as well as blood glucose (2 hours after ingesting 75 g glucose) in persons aged > or = 35 years.FINDINGS: A significant number of subjects reported a family history of hypertension (8.0%), obesity (5.4%), diabetes (3.3%) and stroke (1.4%), with 14.6% of participants reporting any of these NCDs. Subjects with a family history of hypertension had a higher diastolic BP and BMI, higher cholesterol and uric acid concentrations, and an increased risk of obesity. Those with a family history of obesity had a higher BMI and were at increased risk of obesity. Individuals with a family history of diabetes had a higher BMI and higher concentrations of glucose, cholesterol, triglycerides and uric acid, and their risk of obesity and diabetes was increased. Subjects with a family history of stroke had a higher BMI, as well as higher cholesterol, triglyceride and uric acid concentrations.CONCLUSIONS: A family history of hypertension, obesity, diabetes, or stroke was a significant risk factor for obesity and hyperlipidaemia. With increase of age, more pathological manifestations can develop in this high-risk group. Health professionals should therefore utilize every opportunity to include direct family members in health education.",

keywords = "Adult, Diabetes Mellitus/epidemiology, Family Health, Female, Gambia/epidemiology, Genetic Predisposition to Disease, Humans, Hypertension/epidemiology, Medical History Taking, Middle Aged, Obesity/epidemiology, Risk Factors",

author = "{van der Sande}, {M A} and Walraven, {G E} and Milligan, {P J} and Banya, {W A} and Ceesay, {S M} and Nyan, {O A} and McAdam, {K P}",

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year = "2001",

language = "English",

volume = "79",

pages = "321--328",

journal = "Bulletin of the World Health Organization",

issn = "0042-9686",

publisher = "World Health Organization",

number = "4",

}

TY - JOUR

T1 - Family history: an opportunity for early interventions and improved control of hypertension, obesity and diabetes

AU - van der Sande, M A

AU - Walraven, G E

AU - Milligan, P J

AU - Banya, W A

AU - Ceesay, S M

AU - Nyan, O A

AU - McAdam, K P

N1 - FTX; (CC BY 3.0 IGO)

PY - 2001

Y1 - 2001

N2 - OBJECTIVE: To examine whether a family history of high-risk groups for major noncommunicable diseases (NCDs) was a significant risk factor for these conditions among family members in a study population in the Gambia, where strong community and family coherence are important determinants that have to be taken into consideration in promoting lifestyle changes.METHODS: We questioned 5389 adults as to any first-degree family history of major noncommunicable diseases (hypertension, obesity, diabetes and stroke), and measured their blood pressure (BP) and body mass index (BMI). Total blood cholesterol, triglyceride, uric acid, and creatinine concentrations were measured in a stratified subsample, as well as blood glucose (2 hours after ingesting 75 g glucose) in persons aged > or = 35 years.FINDINGS: A significant number of subjects reported a family history of hypertension (8.0%), obesity (5.4%), diabetes (3.3%) and stroke (1.4%), with 14.6% of participants reporting any of these NCDs. Subjects with a family history of hypertension had a higher diastolic BP and BMI, higher cholesterol and uric acid concentrations, and an increased risk of obesity. Those with a family history of obesity had a higher BMI and were at increased risk of obesity. Individuals with a family history of diabetes had a higher BMI and higher concentrations of glucose, cholesterol, triglycerides and uric acid, and their risk of obesity and diabetes was increased. Subjects with a family history of stroke had a higher BMI, as well as higher cholesterol, triglyceride and uric acid concentrations.CONCLUSIONS: A family history of hypertension, obesity, diabetes, or stroke was a significant risk factor for obesity and hyperlipidaemia. With increase of age, more pathological manifestations can develop in this high-risk group. Health professionals should therefore utilize every opportunity to include direct family members in health education.

AB - OBJECTIVE: To examine whether a family history of high-risk groups for major noncommunicable diseases (NCDs) was a significant risk factor for these conditions among family members in a study population in the Gambia, where strong community and family coherence are important determinants that have to be taken into consideration in promoting lifestyle changes.METHODS: We questioned 5389 adults as to any first-degree family history of major noncommunicable diseases (hypertension, obesity, diabetes and stroke), and measured their blood pressure (BP) and body mass index (BMI). Total blood cholesterol, triglyceride, uric acid, and creatinine concentrations were measured in a stratified subsample, as well as blood glucose (2 hours after ingesting 75 g glucose) in persons aged > or = 35 years.FINDINGS: A significant number of subjects reported a family history of hypertension (8.0%), obesity (5.4%), diabetes (3.3%) and stroke (1.4%), with 14.6% of participants reporting any of these NCDs. Subjects with a family history of hypertension had a higher diastolic BP and BMI, higher cholesterol and uric acid concentrations, and an increased risk of obesity. Those with a family history of obesity had a higher BMI and were at increased risk of obesity. Individuals with a family history of diabetes had a higher BMI and higher concentrations of glucose, cholesterol, triglycerides and uric acid, and their risk of obesity and diabetes was increased. Subjects with a family history of stroke had a higher BMI, as well as higher cholesterol, triglyceride and uric acid concentrations.CONCLUSIONS: A family history of hypertension, obesity, diabetes, or stroke was a significant risk factor for obesity and hyperlipidaemia. With increase of age, more pathological manifestations can develop in this high-risk group. Health professionals should therefore utilize every opportunity to include direct family members in health education.

KW - Adult

KW - Diabetes Mellitus/epidemiology

KW - Family Health

KW - Female

KW - Gambia/epidemiology

KW - Genetic Predisposition to Disease

KW - Humans

KW - Hypertension/epidemiology

KW - Medical History Taking

KW - Middle Aged

KW - Obesity/epidemiology

KW - Risk Factors

M3 - A1: Web of Science-article

C2 - 11357211

SN - 0042-9686

VL - 79

SP - 321

EP - 328

JO - Bulletin of the World Health Organization

JF - Bulletin of the World Health Organization

IS - 4

ER -

Family history: an opportunity for early interventions and improved control of hypertension, obesity and diabetes

Abstract

Keywords

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