Field evaluation of SD Bioline Malaria Antigen P.f® for Plasmodium falciparum malaria diagnosis in Nanoro, Burkina Faso

Halidou Tinto, Olivier Sombie, Innocent Valea, Ferdinand Lankoande, Sandrine Yara, Palpouguini Lompo, Marc Tahita, Adama Kazienga, Ouedraogo Sayouba, Sorgho Hermann, Maaike De Crop, Raffaella Ravinetto

Research output: Contribution to journalA2: International peer reviewed article (not A1-type)

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Abstract

A study was conducted to assess the performance of the SD Bioline Malaria Antigen P.f® compared to the ‘’gold standard’’ microscopy as for the diagnosis of Plasmodium falciparum malaria in Nanoro, Burkina Faso. Microscopy and RDT diagnosis were performed on 254 blood samples. 78.09% (189/242) were positive by microscopy compared to 93.8% (227/242) diagnosed by RDT. The RDT test reported 39 false-positive results and one false-negative result. The RDT showed high sensitivity of 99.47% [IC95%: 98.56-100], with
sensitivity increasing with increasing parasite density. RDT specificity was 26.42% [IC95%: 20.86-31.97]. Low specificity limits accuracy for malaria diagnosis. However, in areas of hyperendemic malaria, high sensitivity is preferable to over diagnosis.
Original languageEnglish
JournalAfrican Journal of Parasitology Research
Volume4
Issue number11
Pages (from-to)161-165
Number of pages5
ISSN2343-6549
Publication statusPublished - 2015

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