First dengue co-infection in a Belgian traveler returning from Thailand, July 2013

Lieselotte Cnops, Cristina Domingo, Dorien Van den Bossche, Evilien Vekens, Evelien Brigou, Marjan Van Esbroeck

    Research output: Contribution to journalA1: Web of Science-articlepeer-review


    We report a dengue virus (DENV) co-infection in a Belgian traveler after a three-weeks holiday to Thailand. The patient recovered well without any complication. The infection was diagnosed by NS1 antigen testing and the concurrent presence of serotype DENV1 and DENV2 was demonstrated by reverse transcriptase polymerase chain reaction (RT-PCR) in acute phase serum sampled three days after symptoms onset. The predominant DENV1 serotype was identified as genotype I, lineage Asia-3 by sequencing. To our knowledge, this is the first time that a dengue co-infection is reported in a European traveler. The co-infection accounts for 1.0% of the total number of RT-PCR-positive samples (n=105) diagnosed in the reference laboratory of Belgium between 2008 and 2013. We expect that the number of reports on acute co-infections will increase in the coming years considering the increasing number of regions that are progressively becoming hyperendemic, especially in Southeast Asia.

    Original languageEnglish
    JournalJournal of Clinical Virology
    Issue number4
    Pages (from-to)597-599
    Number of pages3
    Publication statusPublished - 2014


    Dive into the research topics of 'First dengue co-infection in a Belgian traveler returning from Thailand, July 2013'. Together they form a unique fingerprint.

    Cite this