TY - JOUR
T1 - First dengue co-infection in a Belgian traveler returning from Thailand, July 2013
AU - Cnops, Lieselotte
AU - Domingo, Cristina
AU - Van den Bossche, Dorien
AU - Vekens, Evilien
AU - Brigou, Evelien
AU - Van Esbroeck, Marjan
N1 - NPP
PY - 2014
Y1 - 2014
N2 - We report a dengue virus (DENV) co-infection in a Belgian traveler after a three-weeks holiday to Thailand. The patient recovered well without any complication. The infection was diagnosed by NS1 antigen testing and the concurrent presence of serotype DENV1 and DENV2 was demonstrated by reverse transcriptase polymerase chain reaction (RT-PCR) in acute phase serum sampled three days after symptoms onset. The predominant DENV1 serotype was identified as genotype I, lineage Asia-3 by sequencing. To our knowledge, this is the first time that a dengue co-infection is reported in a European traveler. The co-infection accounts for 1.0% of the total number of RT-PCR-positive samples (n=105) diagnosed in the reference laboratory of Belgium between 2008 and 2013. We expect that the number of reports on acute co-infections will increase in the coming years considering the increasing number of regions that are progressively becoming hyperendemic, especially in Southeast Asia.
AB - We report a dengue virus (DENV) co-infection in a Belgian traveler after a three-weeks holiday to Thailand. The patient recovered well without any complication. The infection was diagnosed by NS1 antigen testing and the concurrent presence of serotype DENV1 and DENV2 was demonstrated by reverse transcriptase polymerase chain reaction (RT-PCR) in acute phase serum sampled three days after symptoms onset. The predominant DENV1 serotype was identified as genotype I, lineage Asia-3 by sequencing. To our knowledge, this is the first time that a dengue co-infection is reported in a European traveler. The co-infection accounts for 1.0% of the total number of RT-PCR-positive samples (n=105) diagnosed in the reference laboratory of Belgium between 2008 and 2013. We expect that the number of reports on acute co-infections will increase in the coming years considering the increasing number of regions that are progressively becoming hyperendemic, especially in Southeast Asia.
U2 - 10.1016/j.jcv.2014.10.008
DO - 10.1016/j.jcv.2014.10.008
M3 - A1: Web of Science-article
C2 - 25453334
SN - 1386-6532
VL - 61
SP - 597
EP - 599
JO - Journal of Clinical Virology
JF - Journal of Clinical Virology
IS - 4
ER -