TY - UNPB
T1 - First imported Cases of MPXV Clade Ib in Goma, Democratic Republic of the Congo: Implications for Global Surveillance and Transmission Dynamics
AU - Mukadi-Bamuleka, Daniel
AU - Kinganda-Lusamaki, Eddy
AU - Mulopo-Mukanya, Noella
AU - Amuri-Aziza, Adrienne
AU - O'Toole, Áine
AU - Modadra-Madakpa, Brigitte
AU - Ndongala, Guy Mutombo
AU - Vakaniaki, Emmanuel Hasivirwe
AU - Merritt, Sydney
AU - Kacita, Cris
AU - Maboko, Gaston Lubambo
AU - Makangara-Cigolo, Jean-Claude
AU - Ngimba, Michel
AU - Lokilo, Emmanuel
AU - Pukuta-Simbu, Elisabeth
AU - Luakanda, Gradi
AU - Bodisa-Matamu, Tavia
AU - Kalimuli, Zephanie Paluku
AU - Akil-Bandali, Prince
AU - Kavira, Sifa
AU - Jansen, Daan
AU - Kamaliro, Adèle Kavira
AU - Muhindo-Milonde, Emile
AU - Mufungizi, Jeriel
AU - Hamisi, Yves Birindwa
AU - Kavunga, Hugo
AU - Tshiani, Olivier
AU - Nundu, Sabin S
AU - Liesenborghs, Laurens
AU - Hoff, Nicole A
AU - Nachega, Jean
AU - Shongo, Robert
AU - Ayouba, Ahidjo
AU - Pilarowski, Genay
AU - Mangolopa, Alain Kakule
AU - Ebondo, Amos Kiuka
AU - Low, Nicola
AU - Shaw, Souradet Y
AU - Wilkinson, Sam
AU - Tessema, Sofonias Kifle
AU - Subissi, Lorenzo
AU - Delaporte, Eric
AU - Vercauteren, Koen
AU - Wawina-Bokalanga, Tony
AU - Rimoin, Anne W
AU - Peeters, Martine
AU - Loman, Nicholas
AU - Rambaut, Andrew
AU - Muyembe-Tamfum, Jean-Jacques
AU - Hensley, Lisa E
AU - Kindrachuk, Jason
AU - Mbala-Kingebeni, Placide
AU - Ahuka-Mundeke, Steve
N1 - FTX: CC BY NC ND
PY - 2024/9/16
Y1 - 2024/9/16
N2 - The ongoing national mpox outbreak in the Democratic Republic of the Congo has resulted in more >30,000 suspected cases in the country from January 2023 to August 2024. While these historic case totals have been driven by primarily by zoonosis, the emergence of Clade Ib monkeypox virus (MPXV), which is connected to more sustained human-to-human transmission, has been associated with increasing public health impacts in eastern DRC. First identified in South Kivu province, Clade Ib MPXV has been identified in multiple non-endemic East African countries for the first time. In DRC, there have been concerns over broader Clade Ib expansion in the country that could further complicate containment and mitigation responses. Here, we report the first introductions of Clade Ib into North Kivu province, including within internal displacement camps, with suspected close contact transmission that includes non-intimate contacts and children. These findings demonstrate that mpox case investigations and community messaging campaigns should include considerations for non-sexual contact-mediated transmission of Clade Ib that includes children <15 years.
AB - The ongoing national mpox outbreak in the Democratic Republic of the Congo has resulted in more >30,000 suspected cases in the country from January 2023 to August 2024. While these historic case totals have been driven by primarily by zoonosis, the emergence of Clade Ib monkeypox virus (MPXV), which is connected to more sustained human-to-human transmission, has been associated with increasing public health impacts in eastern DRC. First identified in South Kivu province, Clade Ib MPXV has been identified in multiple non-endemic East African countries for the first time. In DRC, there have been concerns over broader Clade Ib expansion in the country that could further complicate containment and mitigation responses. Here, we report the first introductions of Clade Ib into North Kivu province, including within internal displacement camps, with suspected close contact transmission that includes non-intimate contacts and children. These findings demonstrate that mpox case investigations and community messaging campaigns should include considerations for non-sexual contact-mediated transmission of Clade Ib that includes children <15 years.
U2 - 10.1101/2024.09.12.24313188
DO - 10.1101/2024.09.12.24313188
M3 - Preprint
C2 - 39371169
T3 - medRxiv : the preprint server for health sciences
BT - First imported Cases of MPXV Clade Ib in Goma, Democratic Republic of the Congo: Implications for Global Surveillance and Transmission Dynamics
PB - medRxiv
ER -