Further evidence needed to change policy for the safe and effective radical cure of vivax malaria: insights from the 2019 annual APMEN Vivax Working Group meeting

Varunika Sonani Hapuwatte Ruwanpura; Spike Nowak; Emily Gerth-Guyette; Minerva Theodora; Lek Dysoley; Mebratom Haile; Koen Peeters Grietens; Ric Norman Price; Caroline Anita Lynch; Kamala Thriemer

doi:10.1002/app5.314

Further evidence needed to change policy for the safe and effective radical cure of vivax malaria: insights from the 2019 annual APMEN Vivax Working Group meeting

Varunika Sonani Hapuwatte Ruwanpura, Spike Nowak, Emily Gerth-Guyette, Minerva Theodora, Lek Dysoley, Mebratom Haile, Koen Peeters Grietens, Ric Norman Price, Caroline Anita Lynch, Kamala Thriemer

Socio-ecological Health Research

Research output: Contribution to journal › A1: Web of Science-article › peer-review

14 Downloads (Pure)

Abstract

New diagnostics and treatment options for the radical cure of Plasmodium vivax malaria are now available. At the 2019 annual meeting of the Vivax Working Group of the Asia Pacific Malaria Elimination Network, participants took part in a roundtable discussion to identify further evidence required to introduce these new tools into policy and practice. Key gaps identified were accuracy and reliability of glucose-6-phosphate-dehydrogenase deficiency tests, health system capacity, and feasibility and cost effectiveness of novel treatment strategies in routine clinical practice. As expected, there were differences in the priorities between country partners and researcher partners. To achieve the 2030 target for the regional elimination of malaria, evidence to address these issues should be generated as a matter of priority. Review of global guidelines alongside locally generated data will help to ensure the timely revision and optimisation of national treatment guidelines that will be vital to meet regional elimination goals.

Original language	English
Journal	Asia & The Pacific Policy Studies
Volume	8
Issue number	2
Pages (from-to)	208-242
Number of pages	35
ISSN	2050-2680
DOIs	https://doi.org/10.1002/app5.314
Publication status	Published - 2021

Keywords

Asia Pacific
evidence gaps
malaria elimination
malaria health policy
Plasmodium vivax malaria
policy implementation
radical cure
PREVENT RELAPSE
TAFENOQUINE
RESISTANCE
PRIMAQUINE
LESSONS

Access to Document

10.1002/app5.314Licence: CC BY

2021apps0208Final published version, 15 MBLicence: CC BY

Cite this

Ruwanpura, V. S. H., Nowak, S., Gerth-Guyette, E., Theodora, M., Dysoley, L., Haile, M., Peeters Grietens, K., Price, R. N., Lynch, C. A., & Thriemer, K. (2021). Further evidence needed to change policy for the safe and effective radical cure of vivax malaria: insights from the 2019 annual APMEN Vivax Working Group meeting. Asia & The Pacific Policy Studies, 8(2), 208-242. https://doi.org/10.1002/app5.314

@article{10731776898a4978883018d825b03d81,

title = "Further evidence needed to change policy for the safe and effective radical cure of vivax malaria: insights from the 2019 annual APMEN Vivax Working Group meeting",

abstract = "New diagnostics and treatment options for the radical cure of Plasmodium vivax malaria are now available. At the 2019 annual meeting of the Vivax Working Group of the Asia Pacific Malaria Elimination Network, participants took part in a roundtable discussion to identify further evidence required to introduce these new tools into policy and practice. Key gaps identified were accuracy and reliability of glucose-6-phosphate-dehydrogenase deficiency tests, health system capacity, and feasibility and cost effectiveness of novel treatment strategies in routine clinical practice. As expected, there were differences in the priorities between country partners and researcher partners. To achieve the 2030 target for the regional elimination of malaria, evidence to address these issues should be generated as a matter of priority. Review of global guidelines alongside locally generated data will help to ensure the timely revision and optimisation of national treatment guidelines that will be vital to meet regional elimination goals.",

keywords = "Asia Pacific, evidence gaps, malaria elimination, malaria health policy, Plasmodium vivax malaria, policy implementation, radical cure, PREVENT RELAPSE, TAFENOQUINE, RESISTANCE, PRIMAQUINE, LESSONS",

author = "Ruwanpura, {Varunika Sonani Hapuwatte} and Spike Nowak and Emily Gerth-Guyette and Minerva Theodora and Lek Dysoley and Mebratom Haile and {Peeters Grietens}, Koen and Price, {Ric Norman} and Lynch, {Caroline Anita} and Kamala Thriemer",

note = "FTX; DOAJ; (CC BY 4.0); {\textcopyright} 2021 The Authors. Asia & the Pacific Policy Studies published by Crawford School of Public Policy of the Australian National University and John Wiley & Sons Australia, Ltd.",

year = "2021",

doi = "10.1002/app5.314",

language = "English",

volume = "8",

pages = "208--242",

journal = "Asia & The Pacific Policy Studies",

issn = "2050-2680",

publisher = "John Wiley & Sons",

number = "2",

}

Ruwanpura, VSH, Nowak, S, Gerth-Guyette, E, Theodora, M, Dysoley, L, Haile, M, Peeters Grietens, K, Price, RN, Lynch, CA & Thriemer, K 2021, 'Further evidence needed to change policy for the safe and effective radical cure of vivax malaria: insights from the 2019 annual APMEN Vivax Working Group meeting', Asia & The Pacific Policy Studies, vol. 8, no. 2, pp. 208-242. https://doi.org/10.1002/app5.314

Further evidence needed to change policy for the safe and effective radical cure of vivax malaria: insights from the 2019 annual APMEN Vivax Working Group meeting. / Ruwanpura, Varunika Sonani Hapuwatte; Nowak, Spike; Gerth-Guyette, Emily et al.
In: Asia & The Pacific Policy Studies, Vol. 8, No. 2, 2021, p. 208-242.

Research output: Contribution to journal › A1: Web of Science-article › peer-review

TY - JOUR

T1 - Further evidence needed to change policy for the safe and effective radical cure of vivax malaria: insights from the 2019 annual APMEN Vivax Working Group meeting

AU - Ruwanpura, Varunika Sonani Hapuwatte

AU - Nowak, Spike

AU - Gerth-Guyette, Emily

AU - Theodora, Minerva

AU - Dysoley, Lek

AU - Haile, Mebratom

AU - Peeters Grietens, Koen

AU - Price, Ric Norman

AU - Lynch, Caroline Anita

AU - Thriemer, Kamala

N1 - FTX; DOAJ; (CC BY 4.0); © 2021 The Authors. Asia & the Pacific Policy Studies published by Crawford School of Public Policy of the Australian National University and John Wiley & Sons Australia, Ltd.

PY - 2021

Y1 - 2021

N2 - New diagnostics and treatment options for the radical cure of Plasmodium vivax malaria are now available. At the 2019 annual meeting of the Vivax Working Group of the Asia Pacific Malaria Elimination Network, participants took part in a roundtable discussion to identify further evidence required to introduce these new tools into policy and practice. Key gaps identified were accuracy and reliability of glucose-6-phosphate-dehydrogenase deficiency tests, health system capacity, and feasibility and cost effectiveness of novel treatment strategies in routine clinical practice. As expected, there were differences in the priorities between country partners and researcher partners. To achieve the 2030 target for the regional elimination of malaria, evidence to address these issues should be generated as a matter of priority. Review of global guidelines alongside locally generated data will help to ensure the timely revision and optimisation of national treatment guidelines that will be vital to meet regional elimination goals.

AB - New diagnostics and treatment options for the radical cure of Plasmodium vivax malaria are now available. At the 2019 annual meeting of the Vivax Working Group of the Asia Pacific Malaria Elimination Network, participants took part in a roundtable discussion to identify further evidence required to introduce these new tools into policy and practice. Key gaps identified were accuracy and reliability of glucose-6-phosphate-dehydrogenase deficiency tests, health system capacity, and feasibility and cost effectiveness of novel treatment strategies in routine clinical practice. As expected, there were differences in the priorities between country partners and researcher partners. To achieve the 2030 target for the regional elimination of malaria, evidence to address these issues should be generated as a matter of priority. Review of global guidelines alongside locally generated data will help to ensure the timely revision and optimisation of national treatment guidelines that will be vital to meet regional elimination goals.

KW - Asia Pacific

KW - evidence gaps

KW - malaria elimination

KW - malaria health policy

KW - Plasmodium vivax malaria

KW - policy implementation

KW - radical cure

KW - PREVENT RELAPSE

KW - TAFENOQUINE

KW - RESISTANCE

KW - PRIMAQUINE

KW - LESSONS

U2 - 10.1002/app5.314

DO - 10.1002/app5.314

M3 - A1: Web of Science-article

C2 - 34820128

SN - 2050-2680

VL - 8

SP - 208

EP - 242

JO - Asia & The Pacific Policy Studies

JF - Asia & The Pacific Policy Studies

IS - 2

ER -

Further evidence needed to change policy for the safe and effective radical cure of vivax malaria: insights from the 2019 annual APMEN Vivax Working Group meeting

Abstract

Keywords

Access to Document

Fingerprint

Cite this