Genome analysis of triploid hybrid Leishmania parasite from the neotropics

Frederik Van den Broeck, Senne Heeren, Ilse Maes, Mandy Sanders, James A Cotton, Elisa Cupolillo, Eugenia Alvarez, Lineth Garcia, Maureen Tasia, Alice Marneffe, Jean-Claude Dujardin, Gert Van der Auwera

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We discovered a hybrid Leishmania parasite in Costa Rica that is genetically similar to hybrids from Panama. Genome analyses demonstrated the hybrid is triploid and identified L. braziliensis and L. guyanensis-related strains as parents. Our findings highlight the existence of poorly sampled Leishmania (Viannia) variants infectious to humans.

Original languageEnglish
JournalEmerging Infectious Diseases
Issue number5
Pages (from-to)1076-1078
Number of pages3
Publication statusPublished - 2023


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