Herpes zoster in African patients: a clinical predictor of human immunodeficiency virus infection

R Colebunders, JM Mann, H Francis, B Kapita, I Lebughe, M Ilwaya, N Kakonde, TC Quinn, JW Curran, P Piot

    Research output: Contribution to journalA2: International peer reviewed article (not A1-type)

    Abstract

    A recent episode or a history of herpes zoster was found in 30 (11%) of 284 patients hospitalized with human immunodeficiency virus (HIV) infection at Mama Yemo Hospital, Kinshasa, Zaire. Of 146 African patients with a history of herpes zoster who were referred to us by physicians at the Mama Yemo Hospital, 133 (91%) were HIV seropositive. The clinical characteristics of the herpes zoster episodes did not differ between HIV-seropositive and -seronegative individuals, except that 23% of the HIV-seropositive patients experienced recurrences compared with none of the HIV-seronegative patients (P =. 05). No patient developed a generalized herpes zoster eruption, and only patients with ophthalmic zoster developed related complications. Patients who experienced severe pain during their herpes zoster attack lost more weight than did those who had only minor pain (P =. 0003)
    Original languageEnglish
    JournalJournal of Infectious Diseases
    Volume157
    Pages (from-to)314-318
    ISSN0022-1899
    Publication statusPublished - 1988

    Keywords

    • B780-tropical-medicine
    • Viral diseases
    • AIDS
    • Epidemiology
    • Diagnosis
    • Complications
    • Herpes zoster
    • HIV
    • Seropositivity
    • Congo-Kinshasa
    • Africa-Central

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