HTLV-I infection among prostitutes and pregnant women in Kinshasa, Zaïre: how important is high-risk sexual behavior?

E Delaporte, A Buvé, N Nzilambi, J Goeman, MC Dazza, D Henzel, W Heyward, M St.Louis, P Piot, M Laga

Research output: Contribution to journalA1: Web of Science-article

Abstract

High-risk sexual behavior as risk factor for human T-cell lymphotropic virus type I (HTLV-I) infection was assessed in cross-sectional studies with 1,183 prostitutes and 1,166 pregnant women in Kinshasa, Zaire. Eighty six (7.3%) prostitutes were positive for HTLV-I. The seroprevalence among prostitutes from the regions along the equator was 12.7%, whereas among prostitutes from the other regions it ranged between 0 and 4.3%. In the prostitutes from the high-prevalence regions, but not in the prostitutes from the low-prevalence regions, HTLV-I infection was associated with increasing age [odds ratio (OR) = 1.1 per year increment], active syphilis (OR = 2.3), and human immunodeficiency virus (HIV) infection (OR = 2.0). Forty three (3.7%) pregnant women were HTLV-I seropositive. Among the women from low-prevalence regions, there was no significant difference in HTLV-I seroprevalence between prostitutes (4.3%) and pregnant women (3.5%). In a group of 409 prostitutes who were observed for a mean duration of 23 months, the incidence of HTLV-I infection was 0.7 per 100 women-years, whereas the incidence of HIV infection was 9.8 per 100 women-years. We conclude that in Kinshasa prostitution per se was not associated with an increased risk of HTLV-I infection
Original languageEnglish
JournalJournal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Volume8
Pages (from-to)511-515
ISSN1077-9450
Publication statusPublished - 1995

Keywords

  • B780-tropical-medicine
  • Viral diseases
  • HTLV-1
  • Sexual behavior
  • Prostitutes
  • Pregnancy
  • Women
  • Risk
  • Transmission
  • Seroprevalence
  • Congo-Kinshasa
  • Bandundu
  • Bas-Za‹re
  • Africa-Central

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