Importance and challenges of accurately counting rotavirus deaths in China, 2002

Eileen L Yee; Zhao-Yin Fang; Na Liu; Stephen C Hadler; Xiaofeng Liang; Huaqing Wang; Xu Zhu; Baoming Jiang; Umesh Parashar; Marc-Alain Widdowson; Roger I Glass

doi:10.1016/j.vaccine.2009.08.065

Importance and challenges of accurately counting rotavirus deaths in China, 2002

Eileen L Yee, Zhao-Yin Fang, Na Liu, Stephen C Hadler, Xiaofeng Liang, Huaqing Wang, Xu Zhu, Baoming Jiang, Umesh Parashar, Marc-Alain Widdowson, Roger I Glass

Institute of Tropical Medicine

Research output: Contribution to journal › A1: Web of Science-article › peer-review

Abstract

Rotavirus mortality is an important component of the total burden of rotavirus disease for children under 5 years old, but accurate estimation is difficult for many developing countries. Here we applied a more direct method to improve estimates of rotavirus mortality in China using 2002 Chinese-specific data. Results indicate that in 2002, approximately 13,400 children under 5 years old in China died from rotavirus and 70% of these deaths occur in rural areas. Thus, a national rotavirus immunization program targeting rural areas with high mortality from diarrhoea could dramatically reduce these deaths and urban areas could reduce childhood hospitalizations attributed to rotavirus by 43%.

Original language	English
Journal	Vaccine
Volume	27 Suppl 5
Pages (from-to)	F46-9
ISSN	0264-410X
DOIs	https://doi.org/10.1016/j.vaccine.2009.08.065
Publication status	Published - 2009

Keywords

Child, Preschool
China/epidemiology
Cohort Studies
Cost of Illness
Diarrhea/epidemiology
Humans
Rotavirus Infections/epidemiology
Rotavirus Vaccines/administration & dosage
Rural Population
Sentinel Surveillance

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10.1016/j.vaccine.2009.08.065

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title = "Importance and challenges of accurately counting rotavirus deaths in China, 2002",

abstract = "Rotavirus mortality is an important component of the total burden of rotavirus disease for children under 5 years old, but accurate estimation is difficult for many developing countries. Here we applied a more direct method to improve estimates of rotavirus mortality in China using 2002 Chinese-specific data. Results indicate that in 2002, approximately 13,400 children under 5 years old in China died from rotavirus and 70% of these deaths occur in rural areas. Thus, a national rotavirus immunization program targeting rural areas with high mortality from diarrhoea could dramatically reduce these deaths and urban areas could reduce childhood hospitalizations attributed to rotavirus by 43%.",

keywords = "Child, Preschool, China/epidemiology, Cohort Studies, Cost of Illness, Diarrhea/epidemiology, Humans, Rotavirus Infections/epidemiology, Rotavirus Vaccines/administration & dosage, Rural Population, Sentinel Surveillance",

author = "Yee, {Eileen L} and Zhao-Yin Fang and Na Liu and Hadler, {Stephen C} and Xiaofeng Liang and Huaqing Wang and Xu Zhu and Baoming Jiang and Umesh Parashar and Marc-Alain Widdowson and Glass, {Roger I}",

year = "2009",

doi = "10.1016/j.vaccine.2009.08.065",

language = "English",

volume = "27 Suppl 5",

pages = "F46--9",

journal = "Vaccine",

issn = "0264-410X",

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TY - JOUR

T1 - Importance and challenges of accurately counting rotavirus deaths in China, 2002

AU - Yee, Eileen L

AU - Fang, Zhao-Yin

AU - Liu, Na

AU - Hadler, Stephen C

AU - Liang, Xiaofeng

AU - Wang, Huaqing

AU - Zhu, Xu

AU - Jiang, Baoming

AU - Parashar, Umesh

AU - Widdowson, Marc-Alain

AU - Glass, Roger I

PY - 2009

Y1 - 2009

N2 - Rotavirus mortality is an important component of the total burden of rotavirus disease for children under 5 years old, but accurate estimation is difficult for many developing countries. Here we applied a more direct method to improve estimates of rotavirus mortality in China using 2002 Chinese-specific data. Results indicate that in 2002, approximately 13,400 children under 5 years old in China died from rotavirus and 70% of these deaths occur in rural areas. Thus, a national rotavirus immunization program targeting rural areas with high mortality from diarrhoea could dramatically reduce these deaths and urban areas could reduce childhood hospitalizations attributed to rotavirus by 43%.

AB - Rotavirus mortality is an important component of the total burden of rotavirus disease for children under 5 years old, but accurate estimation is difficult for many developing countries. Here we applied a more direct method to improve estimates of rotavirus mortality in China using 2002 Chinese-specific data. Results indicate that in 2002, approximately 13,400 children under 5 years old in China died from rotavirus and 70% of these deaths occur in rural areas. Thus, a national rotavirus immunization program targeting rural areas with high mortality from diarrhoea could dramatically reduce these deaths and urban areas could reduce childhood hospitalizations attributed to rotavirus by 43%.

KW - Child, Preschool

KW - China/epidemiology

KW - Cohort Studies

KW - Cost of Illness

KW - Diarrhea/epidemiology

KW - Humans

KW - Rotavirus Infections/epidemiology

KW - Rotavirus Vaccines/administration & dosage

KW - Rural Population

KW - Sentinel Surveillance

U2 - 10.1016/j.vaccine.2009.08.065

DO - 10.1016/j.vaccine.2009.08.065

M3 - A1: Web of Science-article

C2 - 19931719

SN - 0264-410X

VL - 27 Suppl 5

SP - F46-9

JO - Vaccine

JF - Vaccine

ER -

Importance and challenges of accurately counting rotavirus deaths in China, 2002

Abstract

Keywords

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