Efficient inactivation of clinical samples containing mycobacteria is crucial for biosafety during shipment and handling. When stored in RNAlater, Mycobacterium tuberculosis H37Ra remains viable, and our results suggest that at -20 °C and 4 °C changes in the mycobacterial transcriptome are possible. Only GTC-TCEP and DNA/RNA Shield inactivate sufficiently for shipment.
|Journal||Diagnostic Microbiology and Infectious Disease|
|Number of pages||3|
|Publication status||Published - 2023|
- Mycobacterium tuberculosis/genetics