Abstract
Efficient inactivation of clinical samples containing mycobacteria is crucial for biosafety during shipment and handling. When stored in RNAlater, Mycobacterium tuberculosis H37Ra remains viable, and our results suggest that at -20 °C and 4 °C changes in the mycobacterial transcriptome are possible. Only GTC-TCEP and DNA/RNA Shield inactivate sufficiently for shipment.
Original language | English |
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Journal | Diagnostic Microbiology and Infectious Disease |
Volume | 106 |
Issue number | 1 |
Pages (from-to) | 115905 |
Number of pages | 3 |
ISSN | 0732-8893 |
DOIs | |
Publication status | Published - 2023 |
Keywords
- DNA
- Humans
- Mycobacterium tuberculosis/genetics
- RNA