In vitro analysis of albendazole sulfoxide enantiomers shows that (+)-(R)-albendazole sulfoxide is the active enantiomer against Taenia solium

A. Paredes; T. de Campo Louren‡o; M. Marzal; A. Rivera; P. Dorny; S. Mahanty; C. Guerra-Giraldez; H.H. García; T.E. Nash; Q.B. Cass

doi:10.1128/AAC.01465-12

In vitro analysis of albendazole sulfoxide enantiomers shows that (+)-(R)-albendazole sulfoxide is the active enantiomer against Taenia solium

A. Paredes, T. de Campo Louren‡o, M. Marzal, A. Rivera, P. Dorny, S. Mahanty, C. Guerra-Giraldez, H.H. García, T.E. Nash, Q.B. Cass

Research output: Contribution to journal › A1: Web of Science-article › peer-review

28 Downloads (Pure)

Original language	English
Journal	Antimicrobial Agents and Chemotherapy
Volume	57
Issue number	2
Pages (from-to)	944-949
Number of pages	6
ISSN	0066-4804
DOIs	https://doi.org/10.1128/AAC.01465-12
Publication status	Published - 2013

Keywords

Helminthic diseases
Animal diseases
Neurocysticercosis
Taenia solium
Pigs
Treatment
Anthelmintics
Albendazole
In vitro
Treatment outcome
Efficacy
Enantiomer
Cysts
Alkaline phosphatase
Antigens
Toxicity
Drug development

Access to Document

10.1128/AAC.01465-12

2013aach0944

http://lib.itg.be/pdf/itg/2013/2013aach0944.pdf

Cite this

Paredes, A., de Campo Louren‡o, T., Marzal, M., Rivera, A., Dorny, P., Mahanty, S., Guerra-Giraldez, C., García, H. H., Nash, T. E., & Cass, Q. B. (2013). In vitro analysis of albendazole sulfoxide enantiomers shows that (+)-(R)-albendazole sulfoxide is the active enantiomer against Taenia solium. Antimicrobial Agents and Chemotherapy, 57(2), 944-949. https://doi.org/10.1128/AAC.01465-12

@article{843666ca3a614081998697b0c4780ddb,

title = "In vitro analysis of albendazole sulfoxide enantiomers shows that (+)-(R)-albendazole sulfoxide is the active enantiomer against Taenia solium",

keywords = "Helminthic diseases, Animal diseases, Neurocysticercosis, Taenia solium, Pigs, Treatment, Anthelmintics, Albendazole, In vitro, Treatment outcome, Efficacy, Enantiomer, Cysts, Alkaline phosphatase, Antigens, Toxicity, Drug development",

author = "A. Paredes and {de Campo Louren‡o}, T. and M. Marzal and A. Rivera and P. Dorny and S. Mahanty and C. Guerra-Giraldez and H.H. Garc{\'i}a and T.E. Nash and Q.B. Cass",

note = "FTX; ITG-B5A; DBM; U-VHELM; JIF; DOI; PDF; DSPACE",

year = "2013",

doi = "10.1128/AAC.01465-12",

language = "English",

volume = "57",

pages = "944--949",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "2",

}

Paredes, A, de Campo Louren‡o, T, Marzal, M, Rivera, A, Dorny, P, Mahanty, S, Guerra-Giraldez, C, García, HH, Nash, TE & Cass, QB 2013, 'In vitro analysis of albendazole sulfoxide enantiomers shows that (+)-(R)-albendazole sulfoxide is the active enantiomer against Taenia solium', Antimicrobial Agents and Chemotherapy, vol. 57, no. 2, pp. 944-949. https://doi.org/10.1128/AAC.01465-12

TY - JOUR

T1 - In vitro analysis of albendazole sulfoxide enantiomers shows that (+)-(R)-albendazole sulfoxide is the active enantiomer against Taenia solium

AU - Paredes, A.

AU - de Campo Louren‡o, T.

AU - Marzal, M.

AU - Rivera, A.

AU - Dorny, P.

AU - Mahanty, S.

AU - Guerra-Giraldez, C.

AU - García, H.H.

AU - Nash, T.E.

AU - Cass, Q.B.

N1 - FTX; ITG-B5A; DBM; U-VHELM; JIF; DOI; PDF; DSPACE

PY - 2013

Y1 - 2013

KW - Helminthic diseases

KW - Animal diseases

KW - Neurocysticercosis

KW - Taenia solium

KW - Pigs

KW - Treatment

KW - Anthelmintics

KW - Albendazole

KW - In vitro

KW - Treatment outcome

KW - Efficacy

KW - Enantiomer

KW - Cysts

KW - Alkaline phosphatase

KW - Antigens

KW - Toxicity

KW - Drug development

U2 - 10.1128/AAC.01465-12

DO - 10.1128/AAC.01465-12

M3 - A1: Web of Science-article

SN - 0066-4804

VL - 57

SP - 944

EP - 949

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 2

ER -