Incidence of influenza-like illness and severe acute respiratory infection during three influenza seasons in Bangladesh, 2008-2010

Eduardo Azziz-Baumgartner, A S M Alamgir, Mustafizur Rahman, Nusrat Homaira, Badrul Munir Sohel, M A Yushuf Sharker, Rashid Uz Zaman, Jacob Dee, Emily S Gurley, Abdullah Al Mamun, Syeda Mah-E-Muneer, Alicia M Fry, Marc-Alain Widdowson, Joseph Bresee, Stephen Lindstrom, Tasnim Azim, Abdullah Brooks, Goutam Podder, M Jahangir Hossain, Mahmudur RahmanStephen P Luby

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: To determine how much influenza contributes to severe acute respiratory illness (SARI), a leading cause of death in children, among people of all ages in Bangladesh.

METHODS: Physicians obtained nasal and throat swabs to test for influenza virus from patients who were hospitalized within 7 days of the onset of severe acute respiratory infection (SARI) or who consulted as outpatients for influenza-like illness (ILI). A community health care utilization survey was conducted to determine the proportion of hospital catchment area residents who sought care at study hospitals and calculate the incidence of influenza using this denominator.

FINDINGS: The estimated incidence of SARI associated with influenza in children < 5 years old was 6.7 (95% confidence interval, CI: 0-18.3); 4.4 (95% CI: 0-13.4) and 6.5 per 1000 person-years (95% CI: 0-8.3/1000) during the 2008, 2009 and 2010 influenza seasons, respectively. The incidence of SARI in people aged ≥ 5 years was 1.1 (95% CI: 0.4-2.0) and 1.3 (95% CI: 0.5-2.2) per 10,000 person-years during 2009 and 2010, respectively. The incidence of medically attended, laboratory-confirmed seasonal influenza in outpatients with ILI was 10 (95% CI: 8-14), 6.6 (95% CI: 5-9) and 17 per 100 person-years (95% CI: 13-22) during the 2008, 2009 and 2010 influenza seasons, respectively.

CONCLUSION: Influenza-like illness is a frequent cause of consultation in the outpatient setting in Bangladesh. Children aged less than  5 years are hospitalized for influenza in greater proportions than children in other age groups.

Original languageEnglish
JournalBulletin of the World Health Organization
Volume90
Issue number1
Pages (from-to)12-9
Number of pages8
ISSN0042-9686
DOIs
Publication statusPublished - 1-Jan-2012

Keywords

  • Adolescent
  • Adult
  • Bangladesh/epidemiology
  • Child
  • Child, Preschool
  • Confidence Intervals
  • Female
  • Health Surveys
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Influenza, Human/epidemiology
  • Inpatients/statistics & numerical data
  • Male
  • Middle Aged
  • Outpatients/statistics & numerical data
  • Population Surveillance
  • Risk Assessment
  • Seasons
  • Severe Acute Respiratory Syndrome/epidemiology
  • Statistics as Topic
  • Time Factors
  • Young Adult

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