Interactive effects of age and respiratory virus on severe lower respiratory infection

SHIVERS Team

doi:10.1017/S0950268818002017

Interactive effects of age and respiratory virus on severe lower respiratory infection

SHIVERS Team

Institute of Tropical Medicine

Research output: Contribution to journal › A1: Web of Science-article › peer-review

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Abstract

We investigated risk factors for severe acute lower respiratory infections (ALRI) among hospitalised children 8 months were at greater risk from influenza-associated ICU admissions and long hospital stay. Children with ADV had increased LOS across all ages. In the first 2 years of life, the effects of different viruses on ALRI severity varies with age. Our findings help to identify specific ages that would most benefit from virus-specific interventions such as vaccines and antivirals.

Original language	English
Journal	Epidemiology and Infection
Volume	146
Issue number	14
Pages (from-to)	1861-1869
Number of pages	9
ISSN	0950-2688
DOIs	https://doi.org/10.1017/S0950268818002017
Publication status	Published - 2018

Keywords

Acute Disease/epidemiology
Age Factors
Female
Hospitalization/statistics & numerical data
Humans
Infant
Infant, Newborn
Intensive Care Units, Neonatal
Intensive Care Units, Pediatric
Male
New Zealand/epidemiology
Respiratory Tract Infections/epidemiology
Risk Factors
Virus Physiological Phenomena

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10.1017/S0950268818002017Licence: Unspecified

2019ebio102520Final published version, 732 KBLicence: Unspecified

Cite this

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title = "Interactive effects of age and respiratory virus on severe lower respiratory infection",

abstract = "We investigated risk factors for severe acute lower respiratory infections (ALRI) among hospitalised children 8 months were at greater risk from influenza-associated ICU admissions and long hospital stay. Children with ADV had increased LOS across all ages. In the first 2 years of life, the effects of different viruses on ALRI severity varies with age. Our findings help to identify specific ages that would most benefit from virus-specific interventions such as vaccines and antivirals.",

keywords = "Acute Disease/epidemiology, Age Factors, Female, Hospitalization/statistics & numerical data, Humans, Infant, Infant, Newborn, Intensive Care Units, Neonatal, Intensive Care Units, Pediatric, Male, New Zealand/epidemiology, Respiratory Tract Infections/epidemiology, Risk Factors, Virus Physiological Phenomena",

author = "{SHIVERS Team} and N Prasad and Trenholme, {A A} and Huang, {Q S} and Thompson, {M G} and N Pierse and Widdowson, {M A} and T Wood and R Seeds and S Taylor and Grant, {C C} and Newbern, {E C}",

note = "FTX; DOAJ",

year = "2018",

doi = "10.1017/S0950268818002017",

language = "English",

volume = "146",

pages = "1861--1869",

journal = "Epidemiology and Infection",

issn = "0950-2688",

publisher = "Cambridge University Press",

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TY - JOUR

T1 - Interactive effects of age and respiratory virus on severe lower respiratory infection

AU - SHIVERS Team

AU - Prasad, N

AU - Trenholme, A A

AU - Huang, Q S

AU - Thompson, M G

AU - Pierse, N

AU - Widdowson, M A

AU - Wood, T

AU - Seeds, R

AU - Taylor, S

AU - Grant, C C

AU - Newbern, E C

N1 - FTX; DOAJ

PY - 2018

Y1 - 2018

N2 - We investigated risk factors for severe acute lower respiratory infections (ALRI) among hospitalised children 8 months were at greater risk from influenza-associated ICU admissions and long hospital stay. Children with ADV had increased LOS across all ages. In the first 2 years of life, the effects of different viruses on ALRI severity varies with age. Our findings help to identify specific ages that would most benefit from virus-specific interventions such as vaccines and antivirals.

AB - We investigated risk factors for severe acute lower respiratory infections (ALRI) among hospitalised children 8 months were at greater risk from influenza-associated ICU admissions and long hospital stay. Children with ADV had increased LOS across all ages. In the first 2 years of life, the effects of different viruses on ALRI severity varies with age. Our findings help to identify specific ages that would most benefit from virus-specific interventions such as vaccines and antivirals.

KW - Acute Disease/epidemiology

KW - Age Factors

KW - Female

KW - Hospitalization/statistics & numerical data

KW - Humans

KW - Infant

KW - Infant, Newborn

KW - Intensive Care Units, Neonatal

KW - Intensive Care Units, Pediatric

KW - Male

KW - New Zealand/epidemiology

KW - Respiratory Tract Infections/epidemiology

KW - Risk Factors

KW - Virus Physiological Phenomena

U2 - 10.1017/S0950268818002017

DO - 10.1017/S0950268818002017

M3 - A1: Web of Science-article

C2 - 30047350

SN - 0950-2688

VL - 146

SP - 1861

EP - 1869

JO - Epidemiology and Infection

JF - Epidemiology and Infection

IS - 14

ER -

Interactive effects of age and respiratory virus on severe lower respiratory infection

Abstract

Keywords

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