Interactive effects of age and respiratory virus on severe lower respiratory infection


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We investigated risk factors for severe acute lower respiratory infections (ALRI) among hospitalised children 8 months were at greater risk from influenza-associated ICU admissions and long hospital stay. Children with ADV had increased LOS across all ages. In the first 2 years of life, the effects of different viruses on ALRI severity varies with age. Our findings help to identify specific ages that would most benefit from virus-specific interventions such as vaccines and antivirals.

Original languageEnglish
JournalEpidemiology and Infection
Issue number14
Pages (from-to)1861-1869
Number of pages9
Publication statusPublished - 2018


  • Acute Disease/epidemiology
  • Age Factors
  • Female
  • Hospitalization/statistics & numerical data
  • Humans
  • Infant
  • Infant, Newborn
  • Intensive Care Units, Neonatal
  • Intensive Care Units, Pediatric
  • Male
  • New Zealand/epidemiology
  • Respiratory Tract Infections/epidemiology
  • Risk Factors
  • Virus Physiological Phenomena


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