Interventions to reduce mortality in sub-Saharan Africa among HIV-infected adults not yet on antiretroviral therapy

K Peterson, J van Griensven, D Huis In 't Veld, R Colebunders

Research output: Contribution to journalA1: Web of Science-article

Abstract

Where antiretroviral therapy is available, the primary source of mortality among HIV-infected people is the delay in starting treatment. Many of these delays occur in the context of care and are modifiable through changes in the protocols followed by healthcare providers for HIV testing, staging and preparation of patients for antiretroviral therapy. A number of potential evidence-based interventions are discussed in the context of sub-Saharan Africa. Included are decentralizing services, initiating counseling on antiretroviral therapy without delay, tracing patients that miss appointments, protecting patient confidentiality, reducing user fees, and providing point-of-care tests for CD4 cell counts, cryptococcal antigen, and for the diagnosis of TB.
Original languageEnglish
JournalExpert Review of Anti-infective Therapy
Volume10
Issue number1
Pages (from-to)43-50
ISSN1478-7210
DOIs
Publication statusPublished - 2012

Keywords

  • B780-tropical-medicine
  • Viral diseases
  • HIV
  • AIDS
  • Control strategies
  • Mortality reduction
  • Interventions
  • Evidence-based
  • Decentralization
  • Health services
  • Voluntary counseling and testing (VCT)
  • VCT
  • Retention
  • Confidentiality
  • User fees
  • Expenditures
  • CD4-positive-T-lymphocytes
  • Cryptococcus
  • Antigens
  • Co-infections
  • Tuberculosis
  • Africa-General

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