Leprosy Agents and Principal Methods of Detection, Identification, and Characterization of the Leprosy Agents

Sofie Braet; Patricia S. Rosa; John S. Spencer; Charlotte Avanzi

doi:10.1007/978-3-031-30893-2_5

Leprosy Agents and Principal Methods of Detection, Identification, and Characterization of the Leprosy Agents

Sofie Braet, Patricia S. Rosa, John S. Spencer, Charlotte Avanzi

Mycobacteriology

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Diagnosis of leprosy is mainly based on the identification of the clinical signs of the disease. Our incapacity to culture the leprosy bacilli in vitro made the steps toward the diagnosis confirmation using laboratory tools difficult, especially in countries where leprosy is not endemic. This chapter aims to provide an overview of the existing laboratory methods to assist clinical diagnosis, their strength, and limitations, based on different applications and various sample types from diagnosis to drug susceptibility. It also aims to list some of the reference literature from the field to guide new investigators and clinicians.

Original language	English
Title of host publication	Hansen’s Disease : A Complete Clinical Guide
Publication date	1-Sept-2023
Edition	1
Pages	45–57
ISBN (Print)	978-3-031-30892-5, 978-3-031-30895-6
ISBN (Electronic)	978-3-031-30893-2
DOIs	https://doi.org/10.1007/978-3-031-30893-2_5
Publication status	Published - 1-Sept-2023

Access to Document

10.1007/978-3-031-30893-2_5

Cite this

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abstract = "Diagnosis of leprosy is mainly based on the identification of the clinical signs of the disease. Our incapacity to culture the leprosy bacilli in vitro made the steps toward the diagnosis confirmation using laboratory tools difficult, especially in countries where leprosy is not endemic. This chapter aims to provide an overview of the existing laboratory methods to assist clinical diagnosis, their strength, and limitations, based on different applications and various sample types from diagnosis to drug susceptibility. It also aims to list some of the reference literature from the field to guide new investigators and clinicians.",

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AB - Diagnosis of leprosy is mainly based on the identification of the clinical signs of the disease. Our incapacity to culture the leprosy bacilli in vitro made the steps toward the diagnosis confirmation using laboratory tools difficult, especially in countries where leprosy is not endemic. This chapter aims to provide an overview of the existing laboratory methods to assist clinical diagnosis, their strength, and limitations, based on different applications and various sample types from diagnosis to drug susceptibility. It also aims to list some of the reference literature from the field to guide new investigators and clinicians.

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