Light microscopic neuropathology of long-term experimental Trypanosoma brucei gambiense infection in the rat

B Chirimwami; EAE Van Marck; JM Brucher; P Mulumba; M Wéry; PLJ Gigase

Light microscopic neuropathology of long-term experimental Trypanosoma brucei gambiense infection in the rat

B Chirimwami
, EAE Van Marck
, JM Brucher
, P Mulumba
, M Wéry
, PLJ Gigase

Institute of Tropical Medicine

Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review

Abstract

A detailed neuropathological description of the brain lesions in rats with terminal Trypanosoma brucei gambiense infection is presented. A generalized meningo-encephalitis was found which is comparable to the lesions encountered in human cases of sleeping sickness. The main lesion is a perivasculitis while demyelinisation areas and neuronal lesions are absent or very scarce.

Original language	English
Journal	Annales de la Société Belge de Médecine Tropicale
Volume	68
Pages (from-to)	195-203
Number of pages	9
ISSN	0365-6527
Publication status	Published - 1988

Keywords

B780-tropical-medicine
Trypanosoma brucei gambiense
Parasitology
Protozoology
Laboratory
Neuropathology
Light microscopy
Congo-Kinshasa
Africa-Central

Cite this

@article{ad6e706496d8422685d44e71be8bc5bc,

title = "Light microscopic neuropathology of long-term experimental Trypanosoma brucei gambiense infection in the rat",

abstract = "A detailed neuropathological description of the brain lesions in rats with terminal Trypanosoma brucei gambiense infection is presented. A generalized meningo-encephalitis was found which is comparable to the lesions encountered in human cases of sleeping sickness. The main lesion is a perivasculitis while demyelinisation areas and neuronal lesions are absent or very scarce.",

keywords = "B780-tropical-medicine, Trypanosoma brucei gambiense, Parasitology, Protozoology, Laboratory, Neuropathology, Light microscopy, Congo-Kinshasa, Africa-Central",

author = "B Chirimwami and \{Van Marck\}, EAE and JM Brucher and P Mulumba and M W{\'e}ry and PLJ Gigase",

note = "available in ITM print journal collection ",

year = "1988",

language = "English",

volume = "68",

pages = "195--203",

journal = "Annales de la Soci{\'e}t{\'e} Belge de M{\'e}decine Tropicale",

issn = "0365-6527",

publisher = "Acco",

}

TY - JOUR

T1 - Light microscopic neuropathology of long-term experimental Trypanosoma brucei gambiense infection in the rat

AU - Chirimwami, B

AU - Van Marck, EAE

AU - Brucher, JM

AU - Mulumba, P

AU - Wéry, M

AU - Gigase, PLJ

N1 - available in ITM print journal collection

PY - 1988

Y1 - 1988

N2 - A detailed neuropathological description of the brain lesions in rats with terminal Trypanosoma brucei gambiense infection is presented. A generalized meningo-encephalitis was found which is comparable to the lesions encountered in human cases of sleeping sickness. The main lesion is a perivasculitis while demyelinisation areas and neuronal lesions are absent or very scarce.

AB - A detailed neuropathological description of the brain lesions in rats with terminal Trypanosoma brucei gambiense infection is presented. A generalized meningo-encephalitis was found which is comparable to the lesions encountered in human cases of sleeping sickness. The main lesion is a perivasculitis while demyelinisation areas and neuronal lesions are absent or very scarce.

KW - B780-tropical-medicine

KW - Trypanosoma brucei gambiense

KW - Parasitology

KW - Protozoology

KW - Laboratory

KW - Neuropathology

KW - Light microscopy

KW - Congo-Kinshasa

KW - Africa-Central

UR - https://www.webofscience.com/wos/woscc/full-record/WOS:A1988R481600002

UR - https://pubmed.ncbi.nlm.nih.gov/3223782/

M3 - A1: Peer-reviewed journal articles

C2 - 3223782

SN - 0365-6527

VL - 68

SP - 195

EP - 203

JO - Annales de la Société Belge de Médecine Tropicale

JF - Annales de la Société Belge de Médecine Tropicale

ER -

Light microscopic neuropathology of long-term experimental Trypanosoma brucei gambiense infection in the rat

Abstract

Keywords

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