Abstract
In a controlled clinical trial we tested the effect of diminazene aceturate (Berenyl, Bayer) in local application against cutaneous leishmaniasis. The study was performed among schoolchildren in Nyala, West-Sudan in 1988 during a major outbreak of cutaneous leishmaniasis in this region. Sixty-six schoolchildren with cutaneous leishmaniasis were enrolled in the study. The children were randomly assigned to either diminazene aceturate (Berenil) or cetrimide 15% + chlorhexidine 1.5% (Savlon) treatment. The study results show a significant faster healing of the ulcers in the children treated with diminazene aceturate (chi-square 7.31, p less than 0.01). We conclude that diminazene aceturate should be considered as a potential topical drug in the treatment of cutaneous leishmaniasis
| Original language | English |
|---|---|
| Journal | Annales de la Société Belge de Médecine Tropicale |
| Volume | 72 |
| Pages (from-to) | 13-19 |
| ISSN | 0365-6527 |
| Publication status | Published - 1992 |
Keywords
- B780-tropical-medicine
- Protozoal diseases
- Leishmaniasis
- Antiprotozoal agents
- Diminazene
- Berenil
- Sudan
- Africa-East