Malaria micro-stratification using routine surveillance data in Western Kenya

Victor A Alegana, Laurissa Suiyanka, Peter M Macharia, Grace Ikahu-Muchangi, Robert W Snow

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Abstract

BACKGROUND: There is an increasing need for finer spatial resolution data on malaria risk to provide micro-stratification to guide sub-national strategic plans. Here, spatial-statistical techniques are used to exploit routine data to depict sub-national heterogeneities in test positivity rate (TPR) for malaria among patients attending health facilities in Kenya.

METHODS: Routine data from health facilities (n = 1804) representing all ages over 24 months (2018-2019) were assembled across 8 counties (62 sub-counties) in Western Kenya. Statistical model-based approaches were used to quantify heterogeneities in TPR and uncertainty at fine spatial resolution adjusting for missingness, population distribution, spatial data structure, month, and type of health facility.

RESULTS: The overall monthly reporting rate was 78.7% (IQR 75.0-100.0) and public-based health facilities were more likely than private facilities to report ≥ 12 months (OR 5.7, 95% CI 4.3-7.5). There was marked heterogeneity in population-weighted TPR with sub-counties in the north of the lake-endemic region exhibiting the highest rates (exceedance probability > 70% with 90% certainty) where approximately 2.7 million (28.5%) people reside. At micro-level the lowest rates were in 14 sub-counties (exceedance probability < 30% with 90% certainty) where approximately 2.2 million (23.1%) people lived and indoor residual spraying had been conducted since 2017.

CONCLUSION: The value of routine health data on TPR can be enhanced when adjusting for underlying population and spatial structures of the data, highlighting small-scale heterogeneities in malaria risk often masked in broad national stratifications. Future research should aim at relating these heterogeneities in TPR with traditional community-level prevalence to improve tailoring malaria control activities at sub-national levels.

Original languageEnglish
Article number22
JournalMalaria Journal
Volume20
Issue number1
ISSN1475-2875
DOIs
Publication statusPublished - 2021

Keywords

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Epidemiological Monitoring
  • Female
  • Health Facilities/statistics & numerical data
  • Humans
  • Kenya/epidemiology
  • Malaria/epidemiology
  • Male
  • Middle Aged
  • Population Surveillance
  • Prevalence
  • Young Adult

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