MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV162P3 in cynomolgus macaques

N. Dereuddre-Bosquet; L. Morellato-Castillo; J. Brouwers; P. Augustijns; K. Bouchemal; G. Ponchel; O.H.P. Ramos; C. Herrera; M. Stefanidou; R. Shattock; L Heyndrickx; G. Vanham; P. Kessler; R. Le Grand; L. Martin

doi:10.1371/journal.ppat.1003071

MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV162P3 in cynomolgus macaques

N. Dereuddre-Bosquet, L. Morellato-Castillo, J. Brouwers, P. Augustijns, K. Bouchemal, G. Ponchel, O.H.P. Ramos, C. Herrera, M. Stefanidou, R. Shattock, L Heyndrickx, G. Vanham, P. Kessler, R. Le Grand, L. Martin

Virology

Research output: Contribution to journal › A1: Web of Science-article › peer-review

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Original language	English
Journal	PLoS Pathogens
Volume	8
Issue number	12
Pages (from-to)	e1003071
ISSN	1553-7366
DOIs	https://doi.org/10.1371/journal.ppat.1003071
Publication status	Published - 2012

Keywords

Viral diseases
HIV-1
AIDS
SHIV
Disease transmission
Prevention
Microbicides
Development
In vivo
Macaques
MiniCD4
Efficacy
Mucosal
Entry inhibitors
Protection
Amino acids
Peptides
Cytotoxicity
Pharmacokinetics
Clinical trials
Sensitivity

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10.1371/journal.ppat.1003071

2012ppate1003071Final published version, 364 KB

Cite this

Dereuddre-Bosquet, N., Morellato-Castillo, L., Brouwers, J., Augustijns, P., Bouchemal, K., Ponchel, G., Ramos, O. H. P., Herrera, C., Stefanidou, M., Shattock, R., Heyndrickx, L., Vanham, G., Kessler, P., Le Grand, R., & Martin, L. (2012). MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV162P3 in cynomolgus macaques. PLoS Pathogens, 8(12), e1003071. https://doi.org/10.1371/journal.ppat.1003071

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author = "N. Dereuddre-Bosquet and L. Morellato-Castillo and J. Brouwers and P. Augustijns and K. Bouchemal and G. Ponchel and O.H.P. Ramos and C. Herrera and M. Stefanidou and R. Shattock and L Heyndrickx and G. Vanham and P. Kessler and {Le Grand}, R. and L. Martin",

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Dereuddre-Bosquet, N, Morellato-Castillo, L, Brouwers, J, Augustijns, P, Bouchemal, K, Ponchel, G, Ramos, OHP, Herrera, C, Stefanidou, M, Shattock, R, Heyndrickx, L, Vanham, G, Kessler, P, Le Grand, R & Martin, L 2012, 'MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV162P3 in cynomolgus macaques', PLoS Pathogens, vol. 8, no. 12, pp. e1003071. https://doi.org/10.1371/journal.ppat.1003071

TY - JOUR

T1 - MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV162P3 in cynomolgus macaques

AU - Dereuddre-Bosquet, N.

AU - Morellato-Castillo, L.

AU - Brouwers, J.

AU - Augustijns, P.

AU - Bouchemal, K.

AU - Ponchel, G.

AU - Ramos, O.H.P.

AU - Herrera, C.

AU - Stefanidou, M.

AU - Shattock, R.

AU - Heyndrickx, L

AU - Vanham, G.

AU - Kessler, P.

AU - Le Grand, R.

AU - Martin, L.

N1 - ITG-B11A; ITG-B12A; DBM; U-VIROL; JIF; E-only; DOI; PDF; DSPACE

PY - 2012

Y1 - 2012

KW - Viral diseases

KW - HIV-1

KW - AIDS

KW - SHIV

KW - Disease transmission

KW - Prevention

KW - Microbicides

KW - Development

KW - In vivo

KW - Macaques

KW - MiniCD4

KW - Efficacy

KW - Mucosal

KW - Entry inhibitors

KW - Protection

KW - Amino acids

KW - Peptides

KW - Cytotoxicity

KW - Pharmacokinetics

KW - Clinical trials

KW - Sensitivity

U2 - 10.1371/journal.ppat.1003071

DO - 10.1371/journal.ppat.1003071

M3 - A1: Web of Science-article

C2 - 23236282

SN - 1553-7366

VL - 8

SP - e1003071

JO - PLoS Pathogens

JF - PLoS Pathogens

IS - 12

ER -