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MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV162P3 in cynomolgus macaques

  • N. Dereuddre-Bosquet
  • , L. Morellato-Castillo
  • , J. Brouwers
  • , P. Augustijns
  • , K. Bouchemal
  • , G. Ponchel
  • , O.H.P. Ramos
  • , C. Herrera
  • , M. Stefanidou
  • , R. Shattock
  • , L Heyndrickx
  • , G. Vanham
  • , P. Kessler
  • , R. Le Grand
  • , L. Martin

Research output: Contribution to journalA1: Peer-reviewed journal articlespeer-review

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Original languageEnglish
JournalPLoS Pathogens
Volume8
Issue number12
Pages (from-to)e1003071
ISSN1553-7366
DOIs
Publication statusPublished - 2012

Keywords

  • Viral diseases
  • HIV-1
  • AIDS
  • SHIV
  • Disease transmission
  • Prevention
  • Microbicides
  • Development
  • In vivo
  • Macaques
  • MiniCD4
  • Efficacy
  • Mucosal
  • Entry inhibitors
  • Protection
  • Amino acids
  • Peptides
  • Cytotoxicity
  • Pharmacokinetics
  • Clinical trials
  • Sensitivity

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