Minimally invasive microbiopsies as an improved sampling method for the diagnosis of cutaneous leishmaniasis

Gemechu Churiso; Saskia van Henten; Lieselotte Cnops; Julia Pollmann; Roma Melkamu; Mulualem Lemma; Amare Kiflie; Helina Fikre; Johan van Griensven; Wim Adriaensen

doi:10.1093/ofid/ofaa364

Minimally invasive microbiopsies as an improved sampling method for the diagnosis of cutaneous leishmaniasis

Gemechu Churiso, Saskia van Henten, Lieselotte Cnops, Julia Pollmann, Roma Melkamu, Mulualem Lemma, Amare Kiflie, Helina Fikre, Johan van Griensven, Wim Adriaensen

Neglected Tropical Diseases

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Abstract

Current sampling methods to diagnose cutaneous leishmaniasis are invasive and painful. An alternative and minimally invasive microbiopsy device was evaluated in a diverse range of cutaneous leishmaniasis lesions in Ethiopia. Using polymerase chain reaction-based diagnosis, the microbiopsy outperformed the routine skin slit sample by detecting more patients while pain scores were significantly lower.

Original language	English
Article number	ofaa364
Journal	Open Forum Infectious Diseases
Volume	7
Issue number	9
Number of pages	3
ISSN	2328-8957
DOIs	https://doi.org/10.1093/ofid/ofaa364
Publication status	Published - 2020

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10.1093/ofid/ofaa364Licence: CC BY-NC-ND

2020ofidofaa364Final published version, 344 KBLicence: CC BY-NC-ND

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title = "Minimally invasive microbiopsies as an improved sampling method for the diagnosis of cutaneous leishmaniasis",

abstract = "Current sampling methods to diagnose cutaneous leishmaniasis are invasive and painful. An alternative and minimally invasive microbiopsy device was evaluated in a diverse range of cutaneous leishmaniasis lesions in Ethiopia. Using polymerase chain reaction-based diagnosis, the microbiopsy outperformed the routine skin slit sample by detecting more patients while pain scores were significantly lower.",

author = "Gemechu Churiso and {van Henten}, Saskia and Lieselotte Cnops and Julia Pollmann and Roma Melkamu and Mulualem Lemma and Amare Kiflie and Helina Fikre and {van Griensven}, Johan and Wim Adriaensen",

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T1 - Minimally invasive microbiopsies as an improved sampling method for the diagnosis of cutaneous leishmaniasis

AU - Churiso, Gemechu

AU - van Henten, Saskia

AU - Cnops, Lieselotte

AU - Pollmann, Julia

AU - Melkamu, Roma

AU - Lemma, Mulualem

AU - Kiflie, Amare

AU - Fikre, Helina

AU - van Griensven, Johan

AU - Adriaensen, Wim

N1 - FTX; DOAJ; (CC BY-NC-ND 4.0); © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

PY - 2020

Y1 - 2020

N2 - Current sampling methods to diagnose cutaneous leishmaniasis are invasive and painful. An alternative and minimally invasive microbiopsy device was evaluated in a diverse range of cutaneous leishmaniasis lesions in Ethiopia. Using polymerase chain reaction-based diagnosis, the microbiopsy outperformed the routine skin slit sample by detecting more patients while pain scores were significantly lower.

AB - Current sampling methods to diagnose cutaneous leishmaniasis are invasive and painful. An alternative and minimally invasive microbiopsy device was evaluated in a diverse range of cutaneous leishmaniasis lesions in Ethiopia. Using polymerase chain reaction-based diagnosis, the microbiopsy outperformed the routine skin slit sample by detecting more patients while pain scores were significantly lower.

U2 - 10.1093/ofid/ofaa364

DO - 10.1093/ofid/ofaa364

M3 - A1: Web of Science-article

C2 - 32939358

SN - 2328-8957

VL - 7

JO - Open Forum Infectious Diseases

JF - Open Forum Infectious Diseases

IS - 9

M1 - ofaa364

ER -

Minimally invasive microbiopsies as an improved sampling method for the diagnosis of cutaneous leishmaniasis

Abstract

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