Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica

Regina Lizundia, Albert Picado, Marlen Cordero, Alejandra Calderón, Stijn Deborggraeve, Victor M Montenegro, Andrea Urbina

    Research output: Contribution to journalA2: International peer reviewed article (not A1-type)

    Abstract

    INTRODUCTION: Chagas disease is a zoonotic disease caused by Trypanosoma cruzi and dogs are one of the main domestic reservoirs.

    MATERIALS AND METHODS: One molecular (OligoC-TesT, Coris Bioconcept) and one serological (T. cruzi-Detect, Inbios) rapid tests were evaluated as infection markers for T. cruzi in 102 dogs living in eight villages endemic for Chagas in Costa Rica.

    RESULTS: T. cruzi-Detect performed well as screening tool with 23.3% positive samples. The large number of invalid results (66.7%) observed in samples tested with OligoC-TesT precluded assessing the use of this new method as epidemiological tool to detect T. cruzi infection in dogs.

    Original languageEnglish
    JournalTropical Parasitology
    Volume4
    Issue number2
    Pages (from-to)111-114
    Number of pages4
    ISSN2229-5070
    DOIs
    Publication statusPublished - 2014

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