Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica

Regina Lizundia; Albert Picado; Marlen Cordero; Alejandra Calderón; Stijn Deborggraeve; Victor M Montenegro; Andrea Urbina

doi:10.4103/2229-5070.138539

Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica

Regina Lizundia, Albert Picado, Marlen Cordero, Alejandra Calderón, Stijn Deborggraeve, Victor M Montenegro, Andrea Urbina

Research output: Contribution to journal › A2: International peer reviewed article (not A1-type) › peer-review

Abstract

INTRODUCTION: Chagas disease is a zoonotic disease caused by Trypanosoma cruzi and dogs are one of the main domestic reservoirs.

MATERIALS AND METHODS: One molecular (OligoC-TesT, Coris Bioconcept) and one serological (T. cruzi-Detect, Inbios) rapid tests were evaluated as infection markers for T. cruzi in 102 dogs living in eight villages endemic for Chagas in Costa Rica.

RESULTS: T. cruzi-Detect performed well as screening tool with 23.3% positive samples. The large number of invalid results (66.7%) observed in samples tested with OligoC-TesT precluded assessing the use of this new method as epidemiological tool to detect T. cruzi infection in dogs.

Original language	English
Journal	Tropical Parasitology
Volume	4
Issue number	2
Pages (from-to)	111-114
Number of pages	4
ISSN	2229-5070
DOIs	https://doi.org/10.4103/2229-5070.138539
Publication status	Published - 2014

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title = "Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica",

abstract = "INTRODUCTION: Chagas disease is a zoonotic disease caused by Trypanosoma cruzi and dogs are one of the main domestic reservoirs.MATERIALS AND METHODS: One molecular (OligoC-TesT, Coris Bioconcept) and one serological (T. cruzi-Detect, Inbios) rapid tests were evaluated as infection markers for T. cruzi in 102 dogs living in eight villages endemic for Chagas in Costa Rica.RESULTS: T. cruzi-Detect performed well as screening tool with 23.3% positive samples. The large number of invalid results (66.7%) observed in samples tested with OligoC-TesT precluded assessing the use of this new method as epidemiological tool to detect T. cruzi infection in dogs.",

author = "Regina Lizundia and Albert Picado and Marlen Cordero and Alejandra Calder{\'o}n and Stijn Deborggraeve and Montenegro, {Victor M} and Andrea Urbina",

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year = "2014",

doi = "10.4103/2229-5070.138539",

language = "English",

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TY - JOUR

T1 - Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica

AU - Lizundia, Regina

AU - Picado, Albert

AU - Cordero, Marlen

AU - Calderón, Alejandra

AU - Deborggraeve, Stijn

AU - Montenegro, Victor M

AU - Urbina, Andrea

N1 - NFT

PY - 2014

Y1 - 2014

N2 - INTRODUCTION: Chagas disease is a zoonotic disease caused by Trypanosoma cruzi and dogs are one of the main domestic reservoirs.MATERIALS AND METHODS: One molecular (OligoC-TesT, Coris Bioconcept) and one serological (T. cruzi-Detect, Inbios) rapid tests were evaluated as infection markers for T. cruzi in 102 dogs living in eight villages endemic for Chagas in Costa Rica.RESULTS: T. cruzi-Detect performed well as screening tool with 23.3% positive samples. The large number of invalid results (66.7%) observed in samples tested with OligoC-TesT precluded assessing the use of this new method as epidemiological tool to detect T. cruzi infection in dogs.

AB - INTRODUCTION: Chagas disease is a zoonotic disease caused by Trypanosoma cruzi and dogs are one of the main domestic reservoirs.MATERIALS AND METHODS: One molecular (OligoC-TesT, Coris Bioconcept) and one serological (T. cruzi-Detect, Inbios) rapid tests were evaluated as infection markers for T. cruzi in 102 dogs living in eight villages endemic for Chagas in Costa Rica.RESULTS: T. cruzi-Detect performed well as screening tool with 23.3% positive samples. The large number of invalid results (66.7%) observed in samples tested with OligoC-TesT precluded assessing the use of this new method as epidemiological tool to detect T. cruzi infection in dogs.

U2 - 10.4103/2229-5070.138539

DO - 10.4103/2229-5070.138539

M3 - A2: International peer reviewed article (not A1-type)

C2 - 25250232

SN - 2229-5070

VL - 4

SP - 111

EP - 114

JO - Tropical Parasitology

JF - Tropical Parasitology

IS - 2

ER -

Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica

Abstract

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