Molecular typing of syphilis-causing strains among human immunodeficiency virus-positive patients in Antwerp, Belgium

Lenka Mikalová; Linda Grillová; Kara Osbak; Michal Strouhal; Chris Kenyon; Tania Crucitti; David Šmajs

doi:10.1097/OLQ.0000000000000600

Molecular typing of syphilis-causing strains among human immunodeficiency virus-positive patients in Antwerp, Belgium

Lenka Mikalová, Linda Grillová, Kara Osbak, Michal Strouhal, Chris Kenyon, Tania Crucitti, David Šmajs

Sexually Transmitted Infections

Research output: Contribution to journal › A1: Web of Science-article › peer-review

Abstract

Centers for Disease Control and Prevention and sequencing-based treponeme typing was used to analyze 72 blood samples, collected from human immunodeficiency virus and syphilis co-infected patients during 2014 to 2015 in Antwerp, Belgium. Twenty-nine (40.3%) isolates were polymerase chain reaction positive for Treponema pallidum, and all tested were macrolide-resistant. Four genotypes were identified by sequencing-based typing including two new genotypes, U4NR8 and SU9R8, whereas enhanced Centers for Disease Control and Prevention typing revealed 7 subtypes.

Original language	English
Journal	Sexually Transmitted Diseases
Volume	44
Issue number	6
Pages (from-to)	376-379
Number of pages	4
ISSN	0148-5717
DOIs	https://doi.org/10.1097/OLQ.0000000000000600
Publication status	Published - 2017

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Journal Article

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10.1097/OLQ.0000000000000600Licence: Unspecified

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abstract = "Centers for Disease Control and Prevention and sequencing-based treponeme typing was used to analyze 72 blood samples, collected from human immunodeficiency virus and syphilis co-infected patients during 2014 to 2015 in Antwerp, Belgium. Twenty-nine (40.3%) isolates were polymerase chain reaction positive for Treponema pallidum, and all tested were macrolide-resistant. Four genotypes were identified by sequencing-based typing including two new genotypes, U4NR8 and SU9R8, whereas enhanced Centers for Disease Control and Prevention typing revealed 7 subtypes.",

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T1 - Molecular typing of syphilis-causing strains among human immunodeficiency virus-positive patients in Antwerp, Belgium

AU - Mikalová, Lenka

AU - Grillová, Linda

AU - Osbak, Kara

AU - Strouhal, Michal

AU - Kenyon, Chris

AU - Crucitti, Tania

AU - Šmajs, David

PY - 2017

Y1 - 2017

N2 - Centers for Disease Control and Prevention and sequencing-based treponeme typing was used to analyze 72 blood samples, collected from human immunodeficiency virus and syphilis co-infected patients during 2014 to 2015 in Antwerp, Belgium. Twenty-nine (40.3%) isolates were polymerase chain reaction positive for Treponema pallidum, and all tested were macrolide-resistant. Four genotypes were identified by sequencing-based typing including two new genotypes, U4NR8 and SU9R8, whereas enhanced Centers for Disease Control and Prevention typing revealed 7 subtypes.

AB - Centers for Disease Control and Prevention and sequencing-based treponeme typing was used to analyze 72 blood samples, collected from human immunodeficiency virus and syphilis co-infected patients during 2014 to 2015 in Antwerp, Belgium. Twenty-nine (40.3%) isolates were polymerase chain reaction positive for Treponema pallidum, and all tested were macrolide-resistant. Four genotypes were identified by sequencing-based typing including two new genotypes, U4NR8 and SU9R8, whereas enhanced Centers for Disease Control and Prevention typing revealed 7 subtypes.

KW - Journal Article

U2 - 10.1097/OLQ.0000000000000600

DO - 10.1097/OLQ.0000000000000600

M3 - A1: Web of Science-article

C2 - 28499290

SN - 0148-5717

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SP - 376

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JO - Sexually Transmitted Diseases

JF - Sexually Transmitted Diseases

IS - 6

ER -

Molecular typing of syphilis-causing strains among human immunodeficiency virus-positive patients in Antwerp, Belgium

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