TY - JOUR
T1 - Neuraminidaseremmers bij verhoogd risico op griepcomplicaties: afgewogen en breed gedragen advies
AU - van Dissel, Jaap T
AU - Coutinho, Roel A
AU - van der Sande, Marianne A B
N1 - NPP
PY - 2009
Y1 - 2009
N2 - It has been suggested that it is unwise to employ neuraminidase inhibitors in order to diminish the risk of influenza-related complications in cases of infection with the new influenza A(H1N1). However, the major argument, i.e. that the beneficial effects shown in the published evidence may be due to age differences between treatment and placebo groups, can easily be refuted. The Netherlands' policy to limit treatment to those patient groups who are considered at high risk of influenza complications is a sound one. In addition, it is endorsed by recent guidelines of the WHO and CDC.
AB - It has been suggested that it is unwise to employ neuraminidase inhibitors in order to diminish the risk of influenza-related complications in cases of infection with the new influenza A(H1N1). However, the major argument, i.e. that the beneficial effects shown in the published evidence may be due to age differences between treatment and placebo groups, can easily be refuted. The Netherlands' policy to limit treatment to those patient groups who are considered at high risk of influenza complications is a sound one. In addition, it is endorsed by recent guidelines of the WHO and CDC.
KW - Age Factors
KW - Antiviral Agents/adverse effects
KW - Centers for Disease Control and Prevention, U.S.
KW - Enzyme Inhibitors/adverse effects
KW - Humans
KW - Influenza A Virus, H1N1 Subtype
KW - Influenza, Human/complications
KW - Neuraminidase/antagonists & inhibitors
KW - Oseltamivir/adverse effects
KW - Practice Guidelines as Topic
KW - Risk Factors
KW - United States
KW - World Health Organization
M3 - A2: Artikel in een internationaal wetenschappelijk tijdschrift met peer review, dat niet inbegrepen is in A1
C2 - 20051160
SN - 0028-2162
VL - 153
JO - Nederlands Tijdschrift voor Geneeskunde
JF - Nederlands Tijdschrift voor Geneeskunde
M1 - B486
ER -