On-going malaria transmission in the Gambia despite high coverage of control interventions: a nationwide cross-sectional survey

Julia Mwesigwa, Joseph Okebe, Muna Affara, Gian Luca Di Tanna, Davis Nwakanma, Omar Janha, Kevin Opondo, Koen Peeters Grietens, Jane Achan, Umberto D'Alessandro

Research output: Contribution to journalA1: Web of Science-article

7 Downloads (Pure)

Abstract

BACKGROUND: As indicators of burden of malaria have substantially decreased in The Gambia, reaching a pre-elimination status may be attainable. Achieving this goal requires in-depth understanding of the current burden of Plasmodium falciparum infection.

METHODS: A nationwide cross-sectional survey was conducted in 2012 to determine the prevalence of P. falciparum infection, and to describe its heterogeneity and associated risk factors. Finger-prick blood samples were collected for microscopy, species-specific PCR and haemoglobin measurement.

RESULTS: A total of 9,094 participants were included and median age was 11.9 years (IQR 5, 28). Overall prevalence of P. falciparum was 16.01 % with marked heterogeneity between sites (4.32-36.75 %) and within villages in each site (1.63-49.13 %). Across all sites, 51.17 % (745/1,456) of infections were asymptomatic and 35.61 % (448/1,258) were sub-microscopic. The odds of P. falciparum infection were higher in older children; 5-15 years (OR = 1.90; 95 % CI 1.60-2.26), adults (OR = 1.48; 95 % CI 1.24-1.78) and participants with moderate anaemia (OR = 1.62; 95 % CI 1.32-1.99).

CONCLUSIONS: The current malaria control interventions are not sufficient to interrupt transmission in The Gambia as malaria prevalence is still relatively high in the eastern part of the country. New interventions aiming at interrupting transmission are needed and should be urgently evaluated.

Original languageEnglish
JournalMalaria Journal
Volume14
Pages (from-to)314
ISSN1475-2875
DOIs
Publication statusPublished - 2015

Fingerprint Dive into the research topics of 'On-going malaria transmission in the Gambia despite high coverage of control interventions: a nationwide cross-sectional survey'. Together they form a unique fingerprint.

Cite this