Post-kala-azar dermal leishmaniasis (PKDL) in visceral leishmaniasis-endemic communities in Bihar, India

Rudra Pratap Singh; Albert Picado; Shahnawaz Alam; Epco Hasker; Shri Prakash Singh; Bart Ostyn; François Chappuis; Shyam Sundar; Marleen Boelaert

doi:10.1111/tmi.12044

Post-kala-azar dermal leishmaniasis (PKDL) in visceral leishmaniasis-endemic communities in Bihar, India

Rudra Pratap Singh, Albert Picado, Shahnawaz Alam, Epco Hasker, Shri Prakash Singh, Bart Ostyn, François Chappuis, Shyam Sundar, Marleen Boelaert

Institute of Tropical Medicine

Research output: Contribution to journal › A1: Web of Science-article › peer-review

Abstract

OBJECTIVE: To assess the prevalence of Post-kala-azar dermal leishmaniasis (PKDL) in 16 visceral leishmaniasis-endemic communities in Bihar, India. METHODS: Three-stage house-to-house survey of 2020 households to identify and confirm PKDL cases. RESULTS: The prevalence of confirmed PKDL cases was 4.4 per 10 000 individuals and 7.8 if probable cases were also considered. The clinical history and treatment of the PKDL cases are discussed in detail. CONCLUSION: PKDL can develop in visceral leishmaniasis patients treated with different anti-leishmanial drugs. Migration of PKDL cases to other villages may expand visceral leishmaniasis-affected areas.

Original language	English
Journal	Tropical Medicine and International Health
ISSN	1360-2276
DOIs	https://doi.org/10.1111/tmi.12044
Publication status	E-pub ahead of print - 2012

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@article{855f6496b6ba4fe68197fa303c89a91f,

title = "Post-kala-azar dermal leishmaniasis (PKDL) in visceral leishmaniasis-endemic communities in Bihar, India",

abstract = "OBJECTIVE: To assess the prevalence of Post-kala-azar dermal leishmaniasis (PKDL) in 16 visceral leishmaniasis-endemic communities in Bihar, India. METHODS: Three-stage house-to-house survey of 2020 households to identify and confirm PKDL cases. RESULTS: The prevalence of confirmed PKDL cases was 4.4 per 10 000 individuals and 7.8 if probable cases were also considered. The clinical history and treatment of the PKDL cases are discussed in detail. CONCLUSION: PKDL can develop in visceral leishmaniasis patients treated with different anti-leishmanial drugs. Migration of PKDL cases to other villages may expand visceral leishmaniasis-affected areas.",

author = "Singh, {Rudra Pratap} and Albert Picado and Shahnawaz Alam and Epco Hasker and Singh, {Shri Prakash} and Bart Ostyn and Fran{\c c}ois Chappuis and Shyam Sundar and Marleen Boelaert",

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year = "2012",

doi = "10.1111/tmi.12044",

language = "English",

journal = "Tropical Medicine and International Health",

issn = "1360-2276",

publisher = "John Wiley & Sons",

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TY - JOUR

T1 - Post-kala-azar dermal leishmaniasis (PKDL) in visceral leishmaniasis-endemic communities in Bihar, India

AU - Singh, Rudra Pratap

AU - Picado, Albert

AU - Alam, Shahnawaz

AU - Hasker, Epco

AU - Singh, Shri Prakash

AU - Ostyn, Bart

AU - Chappuis, François

AU - Sundar, Shyam

AU - Boelaert, Marleen

N1 - CHECK

PY - 2012

Y1 - 2012

N2 - OBJECTIVE: To assess the prevalence of Post-kala-azar dermal leishmaniasis (PKDL) in 16 visceral leishmaniasis-endemic communities in Bihar, India. METHODS: Three-stage house-to-house survey of 2020 households to identify and confirm PKDL cases. RESULTS: The prevalence of confirmed PKDL cases was 4.4 per 10 000 individuals and 7.8 if probable cases were also considered. The clinical history and treatment of the PKDL cases are discussed in detail. CONCLUSION: PKDL can develop in visceral leishmaniasis patients treated with different anti-leishmanial drugs. Migration of PKDL cases to other villages may expand visceral leishmaniasis-affected areas.

AB - OBJECTIVE: To assess the prevalence of Post-kala-azar dermal leishmaniasis (PKDL) in 16 visceral leishmaniasis-endemic communities in Bihar, India. METHODS: Three-stage house-to-house survey of 2020 households to identify and confirm PKDL cases. RESULTS: The prevalence of confirmed PKDL cases was 4.4 per 10 000 individuals and 7.8 if probable cases were also considered. The clinical history and treatment of the PKDL cases are discussed in detail. CONCLUSION: PKDL can develop in visceral leishmaniasis patients treated with different anti-leishmanial drugs. Migration of PKDL cases to other villages may expand visceral leishmaniasis-affected areas.

U2 - 10.1111/tmi.12044

DO - 10.1111/tmi.12044

M3 - A1: Web of Science-article

C2 - 23279744

SN - 1360-2276

JO - Tropical Medicine and International Health

JF - Tropical Medicine and International Health

ER -

Post-kala-azar dermal leishmaniasis (PKDL) in visceral leishmaniasis-endemic communities in Bihar, India

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