Predictors of mortality among tuberculosis-HIV-coinfected persons in Southwest Ethiopia: a case-control study

K. Deribe, A. Yami, A. Deribew, N. Mesfin, Robert Colebunders, J.P. Van geertruyden, M. Woldie, T. Maja

    Research output: Contribution to journalA2: International peer reviewed article (not A1-type)

    Abstract

    Background:Tuberculosis (TB) remains the most common cause of death in people living with HIV/AIDS. The aim of the present study was to identify predictors of mortality in TB-HIV-coinfected patients. Methods:We conducted an unmatched case-control study among a cohort of TB-HIV-coinfected adults who were on antiretroviral therapy (ART). Cases comprised 69 TB-HIV-coinfected patients who died during this period. For each case, we selected 3 (207) TB-HIV-coinfected patients who were alive during the end of the follow-up period. Results:Male sex (odds ratio [OR] = 2.04, 95% confidence interval [CI]: 1.04-4.02), being bedridden at enrollment (OR = 2.84, 95% CI: 1.17-6.89), and cough of more than 2 weeks during initiation of ART (OR = 4.75 95% CI: 2.14-10.56) were the best predictors of mortality among TB-HIV-infected patients. Conclusion:Mortality among TB-HIV-coinfected patients accounted for a considerable number of deaths among the cohort. Patients with cough at ART initiation and with poor functional status should be strictly followed to reduce death.
    Original languageEnglish
    JournalJournal of the International Association of Providers of AIDS Care
    Volume14
    Issue number3
    Pages (from-to)269-273
    Number of pages5
    ISSN2325-9574
    DOIs
    Publication statusPublished - 2015

    Keywords

    • Viral diseases
    • HIV
    • AIDS
    • Co-infections
    • Bacterial diseases
    • Tuberculosis
    • Mycobacterium tuberculosis
    • Epidemiology
    • Mortality
    • Predictors
    • Gender
    • Cough
    • Causes of death
    • Follow-up
    • Ethiopia
    • Africa-East

    Fingerprint

    Dive into the research topics of 'Predictors of mortality among tuberculosis-HIV-coinfected persons in Southwest Ethiopia: a case-control study'. Together they form a unique fingerprint.

    Cite this