Prevention of transfusion-associated HIV transmission in Kinshasa, Zaïre: HIV screening is not enough

H Jäger, B Ngaly, J Perriëns, K Nseka, F Davachi, CM Kabeya, G Rauhaus, G Peyerl, RW Ryder, T Rehle

    Research output: Contribution to journalA1: Web of Science-article

    Abstract

    The purpose of this study was to develop a strategy to reduce transfusion-related HIV transmission which went beyond the limits of routine HIV screening of blood donors. Current blood transfusion practices were assessed in 1044 patients for whom staff physicians had requested a transfusion between 5 September and 19 October, 1988. Children under 5 years of age with malaria, and pregnant women with acute anaemia requiring blood transfusion were the two highest risk groups. Many of the transfusions were given without an obvious medical indication; 22.7% (214 out of 955) of the recipients were transfused without prior laboratory tests [haemoglobin (Hb) or haematocrit (Hct)], 7.2% with Hb greater than 6g/100ml or Hct greater than 25% and 16.6% without clinical signs of severe anaemia (pulse less than 100/min without shortness of breath). The data of this study were used to organize a workshop for all the physicians responsible for blood transfusions in Kinshasa and two nearby health zones. A consensus statement on the indications for blood transfusion was developed. Subsequently, transfusion centres adopted this consensus statement instead of previous guidelines
    Original languageEnglish
    JournalAIDS
    Volume4
    Pages (from-to)571-574
    ISSN0269-9370
    Publication statusPublished - 1990

    Keywords

    • B780-tropical-medicine
    • Viral diseases
    • AIDS
    • HIV
    • Blood transfusion
    • Transmission
    • Screening
    • Congo-Kinshasa
    • Africa-Central

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