Processing phage therapy requests in a Brussels Military Hospital: lessons identified

Sarah Djebara; Christiane Maussen; Daniel De Vos; Maya Merabishvili; Benjamin Damanet; Kim Win Pang; Peggy De Leenheer; Isabella Strachinaru; Patrick Soentjens; Jean-Paul Pirnay

doi:10.3390/v11030265

Processing phage therapy requests in a Brussels Military Hospital: lessons identified

Sarah Djebara, Christiane Maussen, Daniel De Vos, Maya Merabishvili, Benjamin Damanet, Kim Win Pang, Peggy De Leenheer, Isabella Strachinaru, Patrick Soentjens, Jean-Paul Pirnay

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Research output: Contribution to journal › A1: Web of Science-article › peer-review

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Abstract

There is a growing interest in phage therapy as a complementary tool against antimicrobial resistant infections. Since 2007, phages have been used sporadically to treat bacterial infections in well-defined cases in the Queen Astrid military hospital (QAMH) in Brussels, Belgium. In the last two years, external requests for phage therapy have increased significantly. From April 2013 to April 2018, 260 phage therapy requests were addressed to the QAMH. Of these 260 requests, only 15 patients received phage therapy. In this paper, we analyze the phage therapy requests and outcomes in order to improve upon the overall capacity for phage therapy at the QAMH.

Original language	English
Article number	265
Journal	Viruses
Volume	11
Issue number	3
ISSN	1999-4915
DOIs	https://doi.org/10.3390/v11030265
Publication status	Published - 17-Mar-2019

Keywords

Adolescent
Adult
Aged
Anti-Bacterial Agents/therapeutic use
Bacterial Infections/therapy
Belgium
Female
Health Services Needs and Demand
Hospitals, Military
Humans
Male
Middle Aged
Patient Acceptance of Health Care
Patient Preference
Phage Therapy
Young Adult

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10.3390/v11030265Licence: CC BY

2019viru0265Final published version, 5.02 MBLicence: CC BY

Cite this

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title = "Processing phage therapy requests in a Brussels Military Hospital: lessons identified",

abstract = "There is a growing interest in phage therapy as a complementary tool against antimicrobial resistant infections. Since 2007, phages have been used sporadically to treat bacterial infections in well-defined cases in the Queen Astrid military hospital (QAMH) in Brussels, Belgium. In the last two years, external requests for phage therapy have increased significantly. From April 2013 to April 2018, 260 phage therapy requests were addressed to the QAMH. Of these 260 requests, only 15 patients received phage therapy. In this paper, we analyze the phage therapy requests and outcomes in order to improve upon the overall capacity for phage therapy at the QAMH.",

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author = "Sarah Djebara and Christiane Maussen and {De Vos}, Daniel and Maya Merabishvili and Benjamin Damanet and Pang, {Kim Win} and {De Leenheer}, Peggy and Isabella Strachinaru and Patrick Soentjens and Jean-Paul Pirnay",

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Processing phage therapy requests in a Brussels Military Hospital: lessons identified. / Djebara, Sarah; Maussen, Christiane; De Vos, Daniel; Merabishvili, Maya; Damanet, Benjamin; Pang, Kim Win; De Leenheer, Peggy; Strachinaru, Isabella; Soentjens, Patrick; Pirnay, Jean-Paul.

In: Viruses, Vol. 11, No. 3, 265, 17.03.2019.

Research output: Contribution to journal › A1: Web of Science-article › peer-review

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AU - Djebara, Sarah

AU - Maussen, Christiane

AU - De Vos, Daniel

AU - Merabishvili, Maya

AU - Damanet, Benjamin

AU - Pang, Kim Win

AU - De Leenheer, Peggy

AU - Strachinaru, Isabella

AU - Soentjens, Patrick

AU - Pirnay, Jean-Paul

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AB - There is a growing interest in phage therapy as a complementary tool against antimicrobial resistant infections. Since 2007, phages have been used sporadically to treat bacterial infections in well-defined cases in the Queen Astrid military hospital (QAMH) in Brussels, Belgium. In the last two years, external requests for phage therapy have increased significantly. From April 2013 to April 2018, 260 phage therapy requests were addressed to the QAMH. Of these 260 requests, only 15 patients received phage therapy. In this paper, we analyze the phage therapy requests and outcomes in order to improve upon the overall capacity for phage therapy at the QAMH.

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KW - Anti-Bacterial Agents/therapeutic use

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KW - Female

KW - Health Services Needs and Demand

KW - Hospitals, Military

KW - Humans

KW - Male

KW - Middle Aged

KW - Patient Acceptance of Health Care

KW - Patient Preference

KW - Phage Therapy

KW - Young Adult

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