Psychometric evaluation of a new drug-resistant tuberculosis stigma scale

Lisa Redwood, Ellen M H Mitchell, Thu Anh Nguyen, Kerri Viney, Viet Nhung Nguyen, Greg J Fox

Research output: Contribution to journalA1: Web of Science-articlepeer-review


OBJECTIVES: Stigma contributes to diagnostic delay, disease concealment, and reduced wellbeing for people with multidrug-resistant tuberculosis (MDR-TB) and their communities. Despite the negative effects of stigma, there are no scales to measure stigma in people with MDR-TB. This study aimed to develop and validate a scale to measure stigma in people affected by MDR-TB in Vietnam.

STUDY DESIGN AND SETTING: People with rifampicin-resistant (RR)-MDR-TB who had completed at least 3 months of treatment were invited to complete a survey containing 45 draft stigma items. Data analysis included exploratory factor analysis, internal consistency, content, criterion and construct validity, and test-retest reliability.

RESULTS: A total of 315 people with RR/MDR-TB completed the survey. Exploratory factor analysis revealed a 14 item RR/MDR-TB stigma scale with four subscales, including guilt, social exclusion, physical isolation, and blame. Internal consistency and test-retest reliability were good (Cronbach's Alpha = 0.76, ICC = 0.92). Construct validity was adequate with moderate correlations with related constructs.

CONCLUSION: Our RR/MDR-TB Scale demonstrated good psychometric properties in Vietnam. This scale will assist in the measurement of stigma in people with RR/MDR-TB. It will also aid in the evaluation of stigma reduction interventions in people with RR/MDR-TB.

Original languageEnglish
JournalJournal of Clinical Epidemiology
Pages (from-to)101-110
Number of pages10
Publication statusPublished - 2021


  • Adult
  • Antibiotics, Antitubercular/therapeutic use
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Psychometrics/standards
  • Quality of Life/psychology
  • Reproducibility of Results
  • Rifampin/therapeutic use
  • Social Stigma
  • Surveys and Questionnaires
  • Tuberculosis, Multidrug-Resistant/drug therapy
  • Vietnam/epidemiology


Dive into the research topics of 'Psychometric evaluation of a new drug-resistant tuberculosis stigma scale'. Together they form a unique fingerprint.

Cite this