Reprint of "Assessing the impact of a joint human-porcine intervention package for Taenia solium control: Results of a pilot study from northern Lao PDR"

Anna L Okello; Lian Thomas; Phouth Inthavong; Amanda Ash; Boualam Khamlome; Chattouphone Keokamphet; Kim Newberry; Charles G Gauci; Sarah Gabriël; Pierre Dorny; Rc Andrew Thompson; Marshall W Lightowlers; John Allen

doi:10.1016/j.actatropica.2016.11.010

Reprint of "Assessing the impact of a joint human-porcine intervention package for Taenia solium control: Results of a pilot study from northern Lao PDR"

Anna L Okello, Lian Thomas, Phouth Inthavong, Amanda Ash, Boualam Khamlome, Chattouphone Keokamphet, Kim Newberry, Charles G Gauci, Sarah Gabriël, Pierre Dorny, Rc Andrew Thompson, Marshall W Lightowlers, John Allen

Research output: Contribution to journal › A1: Web of Science-article › peer-review

Abstract

Following confirmation that a remote village of approximately 300 inhabitants in northern Lao PDR was hyperendemic for the Neglected Tropical Disease Taenia solium, a pilot human-porcine therapeutic control intervention was implemented between October 2013 and November 2014. Mass drug administration with a three day albendazole 400mg protocol was offered to all eligible humans in October 2013 and March 2014. At these times, and again in October 2014, eligible village pigs received the anti-cysticercosis TSOL18 vaccination and an oral dose of oxfendazole anthelmintic at 30mg/kg, both repeated one month later. Community and individual human taeniasis prevalences were estimated via copro-antigen ELISA of volunteered human faecal samples prior to October 2013, and again in January 2015, in order to examine the short term impact of the intervention.

Original language	English
Journal	Acta Tropica
Volume	165
Pages (from-to)	261-267
Number of pages	7
ISSN	0001-706X
DOIs	https://doi.org/10.1016/j.actatropica.2016.11.010
Publication status	Published - 2017

Keywords

Albendazole/therapeutic use
Animals
Anthelmintics/therapeutic use
Cysticercosis/drug therapy
Enzyme-Linked Immunosorbent Assay
Feces/parasitology
Humans
Laos/epidemiology
Pilot Projects
Prevalence
Sus scrofa/parasitology
Swine
Swine Diseases/drug therapy
Taenia solium/drug effects
Taeniasis/drug therapy
Vaccination

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10.1016/j.actatropica.2016.11.010

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Okello, A. L., Thomas, L., Inthavong, P., Ash, A., Khamlome, B., Keokamphet, C., Newberry, K., Gauci, C. G., Gabriël, S., Dorny, P., Thompson, R. A., Lightowlers, M. W., & Allen, J. (2017). Reprint of "Assessing the impact of a joint human-porcine intervention package for Taenia solium control: Results of a pilot study from northern Lao PDR". Acta Tropica, 165, 261-267. https://doi.org/10.1016/j.actatropica.2016.11.010

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title = "Reprint of {"}Assessing the impact of a joint human-porcine intervention package for Taenia solium control: Results of a pilot study from northern Lao PDR{"}",

abstract = "Following confirmation that a remote village of approximately 300 inhabitants in northern Lao PDR was hyperendemic for the Neglected Tropical Disease Taenia solium, a pilot human-porcine therapeutic control intervention was implemented between October 2013 and November 2014. Mass drug administration with a three day albendazole 400mg protocol was offered to all eligible humans in October 2013 and March 2014. At these times, and again in October 2014, eligible village pigs received the anti-cysticercosis TSOL18 vaccination and an oral dose of oxfendazole anthelmintic at 30mg/kg, both repeated one month later. Community and individual human taeniasis prevalences were estimated via copro-antigen ELISA of volunteered human faecal samples prior to October 2013, and again in January 2015, in order to examine the short term impact of the intervention.",

keywords = "Albendazole/therapeutic use, Animals, Anthelmintics/therapeutic use, Cysticercosis/drug therapy, Enzyme-Linked Immunosorbent Assay, Feces/parasitology, Humans, Laos/epidemiology, Pilot Projects, Prevalence, Sus scrofa/parasitology, Swine, Swine Diseases/drug therapy, Taenia solium/drug effects, Taeniasis/drug therapy, Vaccination",

author = "Okello, {Anna L} and Lian Thomas and Phouth Inthavong and Amanda Ash and Boualam Khamlome and Chattouphone Keokamphet and Kim Newberry and Gauci, {Charles G} and Sarah Gabri{\"e}l and Pierre Dorny and Thompson, {Rc Andrew} and Lightowlers, {Marshall W} and John Allen",

note = "NPP",

year = "2017",

doi = "10.1016/j.actatropica.2016.11.010",

language = "English",

volume = "165",

pages = "261--267",

journal = "Acta Tropica",

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Okello, AL, Thomas, L, Inthavong, P, Ash, A, Khamlome, B, Keokamphet, C, Newberry, K, Gauci, CG, Gabriël, S, Dorny, P, Thompson, RA, Lightowlers, MW & Allen, J 2017, 'Reprint of "Assessing the impact of a joint human-porcine intervention package for Taenia solium control: Results of a pilot study from northern Lao PDR"', Acta Tropica, vol. 165, pp. 261-267. https://doi.org/10.1016/j.actatropica.2016.11.010

TY - JOUR

T1 - Reprint of "Assessing the impact of a joint human-porcine intervention package for Taenia solium control

T2 - Results of a pilot study from northern Lao PDR"

AU - Okello, Anna L

AU - Thomas, Lian

AU - Inthavong, Phouth

AU - Ash, Amanda

AU - Khamlome, Boualam

AU - Keokamphet, Chattouphone

AU - Newberry, Kim

AU - Gauci, Charles G

AU - Gabriël, Sarah

AU - Dorny, Pierre

AU - Thompson, Rc Andrew

AU - Lightowlers, Marshall W

AU - Allen, John

N1 - NPP

PY - 2017

Y1 - 2017

N2 - Following confirmation that a remote village of approximately 300 inhabitants in northern Lao PDR was hyperendemic for the Neglected Tropical Disease Taenia solium, a pilot human-porcine therapeutic control intervention was implemented between October 2013 and November 2014. Mass drug administration with a three day albendazole 400mg protocol was offered to all eligible humans in October 2013 and March 2014. At these times, and again in October 2014, eligible village pigs received the anti-cysticercosis TSOL18 vaccination and an oral dose of oxfendazole anthelmintic at 30mg/kg, both repeated one month later. Community and individual human taeniasis prevalences were estimated via copro-antigen ELISA of volunteered human faecal samples prior to October 2013, and again in January 2015, in order to examine the short term impact of the intervention.

AB - Following confirmation that a remote village of approximately 300 inhabitants in northern Lao PDR was hyperendemic for the Neglected Tropical Disease Taenia solium, a pilot human-porcine therapeutic control intervention was implemented between October 2013 and November 2014. Mass drug administration with a three day albendazole 400mg protocol was offered to all eligible humans in October 2013 and March 2014. At these times, and again in October 2014, eligible village pigs received the anti-cysticercosis TSOL18 vaccination and an oral dose of oxfendazole anthelmintic at 30mg/kg, both repeated one month later. Community and individual human taeniasis prevalences were estimated via copro-antigen ELISA of volunteered human faecal samples prior to October 2013, and again in January 2015, in order to examine the short term impact of the intervention.

KW - Albendazole/therapeutic use

KW - Animals

KW - Anthelmintics/therapeutic use

KW - Cysticercosis/drug therapy

KW - Enzyme-Linked Immunosorbent Assay

KW - Feces/parasitology

KW - Humans

KW - Laos/epidemiology

KW - Pilot Projects

KW - Prevalence

KW - Sus scrofa/parasitology

KW - Swine

KW - Swine Diseases/drug therapy

KW - Taenia solium/drug effects

KW - Taeniasis/drug therapy

KW - Vaccination

U2 - 10.1016/j.actatropica.2016.11.010

DO - 10.1016/j.actatropica.2016.11.010

M3 - A1: Web of Science-article

C2 - 27887694

SN - 0001-706X

VL - 165

SP - 261

EP - 267

JO - Acta Tropica

JF - Acta Tropica

ER -

Reprint of "Assessing the impact of a joint human-porcine intervention package for Taenia solium control: Results of a pilot study from northern Lao PDR"

Abstract

Keywords

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