Screening of strains of the Candida parapsilosis group of the BCCM/IHEM collection by MALDI-TOF MS

M Hendrickx, JS Goffinet, D Swinne, M Detandt

    Research output: Contribution to journalA1: Web of Science-article

    Abstract

    One hundred sixty-three strains stored as Candida parapsilosis in the BCCM/IHEM collection were reidentified based on internal transcribed spacer sequencing: 92% were identified as true C. parapsilosis, while 4.3% and 3% belonged to the closely related species C. metapsilosis and C. orthopsilosis, respectively, providing important epidemiologic information. Furthermore, we showed that matrix-assisted laser desorption ionisation time-of-flight mass spectrometry is a fast method that can discriminate between these species.
    Original languageEnglish
    JournalDiagnostic Microbiology and Infectious Disease
    Volume70
    Issue number4
    Pages (from-to)544-548
    ISSN0732-8893
    DOIs
    Publication statusPublished - 2011

    Keywords

    • B780-tropical-medicine
    • Mycoses
    • Candidiasis
    • Candida parapsilosis
    • Candida metapsilosis
    • Candida orthopsilosis
    • Molecular epidemiology
    • Identification
    • Strains
    • Sequencing
    • Mass spectrometry

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