TY - JOUR
T1 - Specialist laboratory networks as preparedness and response tool - the Emerging Viral Diseases-Expert Laboratory Network and the Chikungunya outbreak, Thailand, 2019
AU - CHIKV-Working Group
AU - Venturi, Giulietta
AU - Aberle, Stephan W.
AU - Avsic-Zupanc, Tatjana
AU - Barzon, Luisa
AU - Batejat, Christoph
AU - Burdino, Elisa
AU - Carletti, Fabrizio
AU - Charrel, Remi
AU - Christova, Iva
AU - Connell, Jeff
AU - Corman, Victor Max
AU - Emmanouil, Mary
AU - Jaaskelainen, Anne J.
AU - Kurolt, Ivan
AU - Lustig, Yaniv
AU - Martinez, Miguel J.
AU - Koopmans, Marion
AU - Nagy, Orsolya
AU - Trung Nguyen, null
AU - Papa, Anna
AU - Perez-Ruiz, Mercedes
AU - Pfeffer, Martin
AU - Protic, Jelena
AU - Reimerink, Johan
AU - Rossini, Giada
AU - Sanchez-Seco Farinas, Maria Paz
AU - Schmidt-Chanasit, Jonas
AU - Soderholm, Sandra
AU - Sudre, Bertrand
AU - Van Esbroeck, Marjan
AU - Reusken, Chantal B.
N1 - FTX; DOAJ; (CC BY 4.0)
PY - 2020
Y1 - 2020
N2 - We illustrate the potential for specialist laboratory networks to be used as preparedness and response tool through rapid collection and sharing of data. Here, the Emerging Viral Diseases-Expert Laboratory Network (EVD-LabNet) and a laboratory assessment of chikungunya virus (CHIKV) in returning European travellers related to an ongoing outbreak in Thailand was used for this purpose. EVD-LabNet rapidly collected data on laboratory requests, diagnosed CHIKV imported cases and sequences generated, and shared among its members and with the European Centre for Disease Prevention and Control. Data across the network showed an increase in CHIKV imported cases during 1 October 2018-30 April 2019 vs the same period in 2018 (172 vs 50), particularly an increase in cases known to be related to travel to Thailand (72 vs 1). Moreover, EVD-LabNet showed that strains were imported from Thailand that cluster with strains of the ECSA-IOL E1 A226 variant emerging in Pakistan in 2016 and involved in the 2017 outbreaks in Italy. CHIKV diagnostic requests increased by 23.6% between the two periods. The impact of using EVD-LabNet or similar networks as preparedness and response tool could be improved by standardisation of the collection, quality and mining of data in routine laboratory management systems.
AB - We illustrate the potential for specialist laboratory networks to be used as preparedness and response tool through rapid collection and sharing of data. Here, the Emerging Viral Diseases-Expert Laboratory Network (EVD-LabNet) and a laboratory assessment of chikungunya virus (CHIKV) in returning European travellers related to an ongoing outbreak in Thailand was used for this purpose. EVD-LabNet rapidly collected data on laboratory requests, diagnosed CHIKV imported cases and sequences generated, and shared among its members and with the European Centre for Disease Prevention and Control. Data across the network showed an increase in CHIKV imported cases during 1 October 2018-30 April 2019 vs the same period in 2018 (172 vs 50), particularly an increase in cases known to be related to travel to Thailand (72 vs 1). Moreover, EVD-LabNet showed that strains were imported from Thailand that cluster with strains of the ECSA-IOL E1 A226 variant emerging in Pakistan in 2016 and involved in the 2017 outbreaks in Italy. CHIKV diagnostic requests increased by 23.6% between the two periods. The impact of using EVD-LabNet or similar networks as preparedness and response tool could be improved by standardisation of the collection, quality and mining of data in routine laboratory management systems.
KW - EXTERNAL QUALITY ASSESSMENT
KW - VIRUS
KW - INFECTION
KW - FOCUS
U2 - 10.2807/1560-7917.ES.2020.25.12.1900438
DO - 10.2807/1560-7917.ES.2020.25.12.1900438
M3 - A1: Web of Science-article
SN - 1560-7917
VL - 25
SP - 31
EP - 37
JO - Eurosurveillance
JF - Eurosurveillance
IS - 13
ER -