'Ten Commandments' for the appropriate use of antibiotics by the practicing physician in an outpatient setting

G Levy-Hara, CF Amábile-Cuevas, I Gould, J Hutchinson, L Abbo, L Saxynger, E Vlieghe, FLL Cardoso, S Methar, S Kanj, N Ohmagari, S Harbarth

    Research output: Contribution to journalA4: Article in journal not included in A1, A2 or A3peer-review


    A multi-national working group on antibiotic stewardship, from the International Society of Chemotherapy, put together ten recommendations to physicians prescribing antibiotics to outpatients. These recommendations are: (1) use antibiotics only when needed; teach the patient how to manage symptoms of non-bacterial infections; (2) select the adequate ATB; precise targeting is better than shotgun therapy; (3) consider pharmacokinetics and pharmacodynamics when selecting an ATB; use the shortest ATB course that has proven clinical efficacy; (4) encourage patients' compliance; (5) use antibiotic combinations only in specific situations; (6) avoid low quality and sub-standard drugs; prevent prescription changes at the drugstore; (7) discourage self-prescription; (8) follow only evidence-based guidelines; beware those sponsored by drug companies; (9) rely (rationally) upon the clinical microbiology lab; and (10) prescribe ATB empirically - but intelligently; know local susceptibility trends, and also surveillance limitations.
    Original languageEnglish
    JournalFrontiers in Microbiology
    Pages (from-to)230
    Number of pages7
    Publication statusPublished - 2011


    • B780-tropical-medicine
    • Treatment
    • Guidelines
    • Recommendations
    • Outpatients
    • Prescription
    • Antibiotics
    • Targeting
    • Pharmacokinetics
    • Short course
    • Clinical
    • Efficacy
    • Compliance
    • Combinations
    • Quality of care
    • Self-medication
    • Evidence-based
    • Susceptibility
    • Surveillance
    • Generics
    • Substandard drugs
    • Global


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