The role of raltegravir in the treatment of HIV-2 infections: evidence from a case series

K. Peterson; J. Ruelle; M. Vekemans; F.P. Siegal; J.R. Deayton; R. Colebunders

doi:10.3851/IMP2303

The role of raltegravir in the treatment of HIV-2 infections: evidence from a case series

K. Peterson, J. Ruelle, M. Vekemans, F.P. Siegal, J.R. Deayton, R. Colebunders

Research output: Contribution to journal › A1: Web of Science-article › peer-review

Abstract

We describe five patients with HIV-2 infection (four antiretroviral-experienced and one antiretroviral-naive) treated with a regimen containing raltegravir. All responded to treatment as demonstrated by viral load and CD4(+) T-cell count monitoring. Our series confirms the clinical effectiveness of raltegravir in HIV-2-infected patients when given with other antiretrovirals to which the virus is susceptible.

Original language	English
Journal	Antiviral Therapy
Volume	17
Issue number	6
Pages (from-to)	1097-1100
Number of pages	4
ISSN	1359-6535
DOIs	https://doi.org/10.3851/IMP2303
Publication status	Published - 2012

Keywords

Viral diseases
HIV-2
AIDS
Case reports
HAART
Antiretrovirals
Raltegravir
Viral load
CD4 lymphocyte count
Treatment outcome
Effectiveness
Monitoring

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10.3851/IMP2303

http://www.ncbi.nlm.nih.gov/pubmed/22892365

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title = "The role of raltegravir in the treatment of HIV-2 infections: evidence from a case series",

abstract = "We describe five patients with HIV-2 infection (four antiretroviral-experienced and one antiretroviral-naive) treated with a regimen containing raltegravir. All responded to treatment as demonstrated by viral load and CD4(+) T-cell count monitoring. Our series confirms the clinical effectiveness of raltegravir in HIV-2-infected patients when given with other antiretrovirals to which the virus is susceptible.",

keywords = "Viral diseases, HIV-2, AIDS, Case reports, HAART, Antiretrovirals, Raltegravir, Viral load, CD4 lymphocyte count, Treatment outcome, Effectiveness, Monitoring",

author = "K. Peterson and J. Ruelle and M. Vekemans and F.P. Siegal and J.R. Deayton and R. Colebunders",

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T1 - The role of raltegravir in the treatment of HIV-2 infections: evidence from a case series

AU - Peterson, K.

AU - Ruelle, J.

AU - Vekemans, M.

AU - Siegal, F.P.

AU - Deayton, J.R.

AU - Colebunders, R.

N1 - NPP; ITG-C1B; ITG-C3A; ITG-CLA; DCS; U-HIVCLI; U-TRAVC; JIF; DOI; Abstract; DSPACE

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N2 - We describe five patients with HIV-2 infection (four antiretroviral-experienced and one antiretroviral-naive) treated with a regimen containing raltegravir. All responded to treatment as demonstrated by viral load and CD4(+) T-cell count monitoring. Our series confirms the clinical effectiveness of raltegravir in HIV-2-infected patients when given with other antiretrovirals to which the virus is susceptible.

AB - We describe five patients with HIV-2 infection (four antiretroviral-experienced and one antiretroviral-naive) treated with a regimen containing raltegravir. All responded to treatment as demonstrated by viral load and CD4(+) T-cell count monitoring. Our series confirms the clinical effectiveness of raltegravir in HIV-2-infected patients when given with other antiretrovirals to which the virus is susceptible.

KW - Viral diseases

KW - HIV-2

KW - AIDS

KW - Case reports

KW - HAART

KW - Antiretrovirals

KW - Raltegravir

KW - Viral load

KW - CD4 lymphocyte count

KW - Treatment outcome

KW - Effectiveness

KW - Monitoring

U2 - 10.3851/IMP2303

DO - 10.3851/IMP2303

M3 - A1: Web of Science-article

C2 - 22892365

SN - 1359-6535

VL - 17

SP - 1097

EP - 1100

JO - Antiviral Therapy

JF - Antiviral Therapy

IS - 6

ER -

The role of raltegravir in the treatment of HIV-2 infections: evidence from a case series

Abstract

Keywords

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