The role of temperature and humidity on seasonal influenza in tropical areas: Guatemala, El Salvador and Panama, 2008-2013

Radina P Soebiyanto, Wilfrido Clara, Jorge Jara, Leticia Castillo, Oscar Rene Sorto, Sidia Marinero, María E Barnett de Antinori, John P McCracken, Marc-Alain Widdowson, Eduardo Azziz-Baumgartner, Richard K Kiang

Research output: Contribution to journalArticle

Abstract

BACKGROUND: The role of meteorological factors on influenza transmission in the tropics is less defined than in the temperate regions. We assessed the association between influenza activity and temperature, specific humidity and rainfall in 6 study areas that included 11 departments or provinces within 3 tropical Central American countries: Guatemala, El Salvador and Panama.

METHOD/FINDINGS: Logistic regression was used to model the weekly proportion of laboratory-confirmed influenza positive samples during 2008 to 2013 (excluding pandemic year 2009). Meteorological data was obtained from the Tropical Rainfall Measuring Mission satellite and the Global Land Data Assimilation System. We found that specific humidity was positively associated with influenza activity in El Salvador (Odds Ratio (OR) and 95% Confidence Interval of 1.18 (1.07-1.31) and 1.32 (1.08-1.63)) and Panama (OR = 1.44 (1.08-1.93) and 1.97 (1.34-2.93)), but negatively associated with influenza activity in Guatemala (OR = 0.72 (0.6-0.86) and 0.79 (0.69-0.91)). Temperature was negatively associated with influenza in El Salvador's west-central departments (OR = 0.80 (0.7-0.91)) whilst rainfall was positively associated with influenza in Guatemala's central departments (OR = 1.05 (1.01-1.09)) and Panama province (OR = 1.10 (1.05-1.14)). In 4 out of the 6 locations, specific humidity had the highest contribution to the model as compared to temperature and rainfall. The model performed best in estimating 2013 influenza activity in Panama and west-central El Salvador departments (correlation coefficients: 0.5-0.9).

CONCLUSIONS/SIGNIFICANCE: The findings highlighted the association between influenza activity and specific humidity in these 3 tropical countries. Positive association with humidity was found in El Salvador and Panama. Negative association was found in the more subtropical Guatemala, similar to temperate regions. Of all the study locations, Guatemala had annual mean temperature and specific humidity that were lower than the others.

Original languageEnglish
JournalPLoS ONE
Volume9
Issue number6
Pages (from-to)e100659
ISSN1932-6203
DOIs
Publication statusPublished - 2014

Keywords

  • Guatemala/epidemiology
  • Humans
  • Humidity
  • Influenza A virus/isolation & purification
  • Influenza, Human/epidemiology
  • Meteorological Concepts
  • Panama/epidemiology
  • Seasons
  • Temperature
  • Time Factors
  • Tropical Climate

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