Three doses of BNT162b2 vaccine confer neutralising antibody capacity against the SARS-CoV-2 Omicron variant

Kevin K Ariën; Leo Heyndrickx; Johan Michiels; Katleen Vereecken; Kurt Van Lent; Sandra Coppens; Betty Willems; Pieter Pannus; Geert A Martens; Marjan Van Esbroeck; Maria E Goossens; Arnaud Marchant; Koen Bartholomeeusen; Isabelle Desombere

doi:10.1038/s41541-022-00459-z

Three doses of BNT162b2 vaccine confer neutralising antibody capacity against the SARS-CoV-2 Omicron variant

Kevin K Ariën, Leo Heyndrickx, Johan Michiels, Katleen Vereecken, Kurt Van Lent, Sandra Coppens, Betty Willems, Pieter Pannus, Geert A Martens, Marjan Van Esbroeck, Maria E Goossens, Arnaud Marchant, Koen Bartholomeeusen, Isabelle Desombere

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Abstract

We report the levels of neutralising antibodies against Wuhan, Delta and Omicron variants in unimmunized infected (group 1), immunised and boosted (group 2) and infected immunised and boosted (group 3) adult individuals. Our observations support the rapid administration of a booster vaccine dose to prevent infection and disease caused by Omicron.

Original language	English
Article number	35
Journal	Vaccines
Volume	7
Issue number	1
Number of pages	3
ISSN	2076-393X
DOIs	https://doi.org/10.1038/s41541-022-00459-z
Publication status	Published - 2022

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10.1038/s41541-022-00459-zLicence: CC BY

2022vacc0035Final published version, 687 KBLicence: CC BY

ImmCoV: Are SARS-CoV-2 specific antibodies a correlate for protection?)
Ariën, K. & Janssens, N.
Research Fund - Flanders
22/05/20 → 31/05/23
Project: Research Project

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Ariën, K. K., Heyndrickx, L., Michiels, J., Vereecken, K., Van Lent, K., Coppens, S., Willems, B., Pannus, P., Martens, G. A., Van Esbroeck, M., Goossens, M. E., Marchant, A., Bartholomeeusen, K., & Desombere, I. (2022). Three doses of BNT162b2 vaccine confer neutralising antibody capacity against the SARS-CoV-2 Omicron variant. Vaccines, 7(1), Article 35. https://doi.org/10.1038/s41541-022-00459-z

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abstract = "We report the levels of neutralising antibodies against Wuhan, Delta and Omicron variants in unimmunized infected (group 1), immunised and boosted (group 2) and infected immunised and boosted (group 3) adult individuals. Our observations support the rapid administration of a booster vaccine dose to prevent infection and disease caused by Omicron.",

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doi = "10.1038/s41541-022-00459-z",

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Ariën, KK, Heyndrickx, L, Michiels, J , Vereecken, K , Van Lent, K , Coppens, S , Willems, B, Pannus, P, Martens, GA, Van Esbroeck, M, Goossens, ME, Marchant, A, Bartholomeeusen, K & Desombere, I 2022, 'Three doses of BNT162b2 vaccine confer neutralising antibody capacity against the SARS-CoV-2 Omicron variant', Vaccines, vol. 7, no. 1, 35. https://doi.org/10.1038/s41541-022-00459-z

TY - JOUR

T1 - Three doses of BNT162b2 vaccine confer neutralising antibody capacity against the SARS-CoV-2 Omicron variant

AU - Ariën, Kevin K

AU - Heyndrickx, Leo

AU - Michiels, Johan

AU - Vereecken, Katleen

AU - Van Lent, Kurt

AU - Coppens, Sandra

AU - Willems, Betty

AU - Pannus, Pieter

AU - Martens, Geert A

AU - Van Esbroeck, Marjan

AU - Goossens, Maria E

AU - Marchant, Arnaud

AU - Bartholomeeusen, Koen

AU - Desombere, Isabelle

PY - 2022

Y1 - 2022

N2 - We report the levels of neutralising antibodies against Wuhan, Delta and Omicron variants in unimmunized infected (group 1), immunised and boosted (group 2) and infected immunised and boosted (group 3) adult individuals. Our observations support the rapid administration of a booster vaccine dose to prevent infection and disease caused by Omicron.

AB - We report the levels of neutralising antibodies against Wuhan, Delta and Omicron variants in unimmunized infected (group 1), immunised and boosted (group 2) and infected immunised and boosted (group 3) adult individuals. Our observations support the rapid administration of a booster vaccine dose to prevent infection and disease caused by Omicron.

U2 - 10.1038/s41541-022-00459-z

DO - 10.1038/s41541-022-00459-z

M3 - A1: Web of Science-article

C2 - 35260578

SN - 2076-393X

VL - 7

JO - Vaccines

JF - Vaccines

IS - 1

M1 - 35

ER -

Three doses of BNT162b2 vaccine confer neutralising antibody capacity against the SARS-CoV-2 Omicron variant

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ImmCoV: Are SARS-CoV-2 specific antibodies a correlate for protection?)

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