Through the dark continent: African trypanosome development in the tsetse fly

B. Rotureau, J. Van Den Abbeele

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    African trypanosomes are unicellular flagellated parasites causing trypanosomiases in Africa, a group of severe diseases also known as sleeping sickness in human and nagana in cattle. These parasites are almost exclusively transmitted by the bite of the tsetse fly. In this review, we describe and compare the three developmental programs of the main trypanosome species impacting human and animal health, with focus on the most recent observations. From here, some reflections are made on research issues concerning trypanosome developmental biology in the tsetse fly that are to be addressed in the future.
    Original languageEnglish
    JournalFrontiers in Cellular and Infection Microbiology
    Issue number53
    Pages (from-to)1-7
    Number of pages7
    Publication statusPublished - 2013


    • Protozoal diseases
    • Nagana
    • Sleeping sickness
    • Trypanosoma brucei gambiense
    • Trypanosoma brucei brucei
    • Trypanosoma vivax
    • Trypanosoma congolense
    • Vectors
    • Tsetse flies
    • Glossina morsitans
    • Cattle
    • Development
    • Life cycles
    • Epimastigote
    • Trypomastigote
    • Staging
    • Africa-General


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