Translating Guidelines, Protocols, and Care Pathways for Hypertension Into Effective Program Implementation

P Ordunez, SY Angell, DJ Dipette, J Brettler, NRC Campbell, MG Jaffe, N Chapman, A Rosende, GM Ku, E Londono, DJ Pineiro, PK Whelton

Research output: Contribution to journalA1: Web of Science-articlepeer-review

Abstract

BACKGROUND
Inconsistent terminology and conceptual overlap among clinical practice guidelines, treatment protocols, and care pathways can lead to confusion in program design and implementation.

METHODS
Drawing on the implementation experience of HEARTS in the Americas—the largest regional adaptation of the WHO Global HEARTS Initiative—this communication describes the characteristics, functions, and interrelationships of clinical practice guidelines, treatment protocols, and care pathways. It outlines their respective roles in development, approval, and execution to clarify their contributions to both health system organization and clinical practice.

RESULTS
Clinical practice guidelines are composed of evidence-based recommendations grounded in rigorous scientific evaluation to support clinical decision-making. Care pathways serve as implementation tools that translate guidelines into standardized, multidisciplinary plans that organize hypertension management, facilitate task-sharing, and engage patients. Embedded within pathways, treatment protocols offer a simplified, step-by-step approach tailored to most patients, specifying a limited set of medications and dosages to ensure timely blood pressure control, reduce therapeutic inertia, and promote consistent care delivery.

CONCLUSIONS
Clarifying the distinctions and synergies among guidelines, protocols, and care pathways might enhance alignment between clinical guidance and service delivery, supporting effective implementation and scale-up of hypertension and chronic disease management programs.
Original languageEnglish
Article numberhpaf103
JournalAmerican Journal of Hypertension
Number of pages5
ISSN0895-7061
DOIs
Publication statusE-pub ahead of print - 12-Aug-2025

Keywords

  • Blood pressure
  • Care pathways
  • Clinical practice guidelines
  • Hypertension
  • Primary care
  • Quality improvement
  • Treatment protocols

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