Two mutations in dihydrofolate reductase combined with one in the dihydropteroate synthase gene predict sulphadoxine-pyrimethamine parasitological failure in Ugandan children with uncomplicated falciparum malaria

AO Talisuna, A Nalunkuma-Kazibwe, P Langi, TK Mutabingwa, WW Watkins, E Van Marck, TG Egwang, U D'Alessandro

    Research output: Contribution to journalA1: Web of Science-article

    Original languageEnglish
    JournalInfection, Genetics and Evolution
    Volume4
    Issue number2
    Pages (from-to)321-327
    ISSN1567-1348
    DOIs
    Publication statusPublished - 2004

    Keywords

    • B780-tropical-medicine
    • Protozoal diseases
    • Malaria
    • Plasmodium falciparum
    • Antimalarials
    • Sulfadoxine-pyrimethamine
    • Drug resistance
    • Prediction
    • Risk populations
    • Screening
    • In vivo
    • Molecular markers
    • Point mutations
    • Dihydrofolate reductase
    • Dihydropteroate synthase
    • Uganda
    • Africa-East

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