Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment

Antimycobacterial Susceptibility T

Research output: Contribution to journalA1: Web of Science-articlepeer-review


Inappropriately high breakpoints have resulted in systematic false-susceptible AST results to anti-TB drugs. MIC, PK/PD and clinical outcome data should be combined when setting breakpoints to minimise the emergence and spread of antimicrobial resistance. https://bit.ly/3i43wb6

Original languageEnglish
Article number2200166
JournalEuropean Respiratory Journal
Issue number4
Number of pages11
Publication statusPublished - 2022


  • Antitubercular Agents/pharmacology
  • Drug Resistance, Bacterial
  • Drug Resistance, Multiple, Bacterial
  • Humans
  • Microbial Sensitivity Tests
  • Mycobacterium tuberculosis
  • Tuberculosis, Multidrug-Resistant/diagnosis

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