Uptake and effectiveness of two-drug compared with three-drug antiretroviral regimens among HIV-positive individuals in Europe

EuroSIDA Study

Research output: Contribution to journalA1: Web of Science-article

Abstract

Objective: To assess the use of two-drug antiretroviral regimens (2DR) and virologic and immunologic outcomes compared with three-drug regimens (3DR) in the EuroSIDA cohort. Design: Multicentre, prospective cohort study. Methods: Logistic regression was used to analyse the uptake and outcomes among HIV-positive individuals who started or switched to a 2DR compared with those on a 3DR. Virologic outcomes were assessed on-treatment as the proportion of individuals with controlled viral load (

Original languageEnglish
JournalAIDS
Volume33
Issue number13
Pages (from-to)2013-2024
Number of pages12
ISSN0269-9370
DOIs
Publication statusPublished - 2019

Keywords

  • combination antiretroviral treatment
  • dual therapy
  • HIV
  • nucleot(s)ide reverse transcriptase inhibitor-sparing regimens
  • simplification
  • two-drug regimens
  • ATAZANAVIR/RITONAVIR PLUS LAMIVUDINE
  • REVERSE-TRANSCRIPTASE INHIBITOR
  • OPEN-LABEL
  • RANDOMIZED-TRIAL
  • NON-INFERIORITY
  • INFECTED PATIENTS
  • TRIPLE THERAPY
  • DUAL THERAPY
  • EMTRICITABINE
  • MAINTENANCE

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